One of the last frontiers in pediatric studies is those studies directed at the care of the
maternal-placental-fetal unit. Because of the concern for teratogenicity and the possibility of …

The current status, recent advances, and future trends in perinatal pharmacology are
highlighted, with emphasis on the individualization of drug regimens in preterm and term …

The article discusses new era of fetal clinical pharmacology including understanding drug
disposition and effect in the fetus will come in several stages. Topics include the exposure of …

Clinical pharmacology is a branch of the field of pharmacology that evolved following the
recognition that the nature, duration, and intensity of drug action depend on both the intrinsic …

The article discusses the research community on National Institute of Child Health and
Human Development's (NICHD) Obstetric and Pediatric Pharmacology Branch (OPPTB) …

The data available to inform pregnant and lactating women about drug safety and efficacy
are woefully inadequate. This lack of information encompasses every aspect of …

Use of pharmacotherapy during pregnancy is common and increasing. Physiologic changes
during pregnancy may significantly alter the overall systemic drug exposure, necessitating …

In the eight years following the last issue of Seminars in Fetal and Neonatal Medicine
devoted to perinatal pharmacology, significant progress has been made. To illustrate this, a …

During the 1960s, the teratogenic effects of thalidomide focused attention upon the fetus as
the unintended recipient of various substances transferred from the maternal circulation …

Developmental pharmacology is a science that does not start at birth, but rather
preconceptionally. However, training for obstetricians, perinatologists, and neonatologists in …