Myocardial fibrosis in congenital and pediatric heart disease

J Tian, X An, L Niu - Experimental and therapeutic …, 2017 - spandidos-publications.com
Cardiac fibrosis is a common phenomenon in different types of heart diseases, such as
ischemic heart disease, inherited cardiomyopathy mutations, diabetes, and ageing and is …

Cardiac fibrosis

NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

Myocardial fibrosis in congenital heart disease

B Gordon, V González-Fernández… - Frontiers in …, 2022 - frontiersin.org
Myocardial fibrosis resulting from the excessive deposition of collagen fibers through the
myocardium is a common histopathologic finding in a wide range of cardiovascular …

The pathogenesis of cardiac fibrosis

P Kong, P Christia, NG Frangogiannis - Cellular and molecular life …, 2014 - Springer
Cardiac fibrosis is characterized by net accumulation of extracellular matrix proteins in the
cardiac interstitium, and contributes to both systolic and diastolic dysfunction in many …

[HTML][HTML] Current understanding of fibrosis in genetic cardiomyopathies

TR Eijgenraam, HHW Silljé, RA de Boer - Trends in cardiovascular …, 2020 - Elsevier
Myocardial fibrosis is the excessive deposition of extracellular matrix proteins, including
collagens, in the heart. In cardiomyopathies, the formation of interstitial fibrosis and/or …

Myocardial fibrosis in congenital heart disease

RH Rathod, AJ Powell, T Geva - Circulation Journal, 2016 - jstage.jst.go.jp
Myocardial fibrosis is common in patients with congenital heart disease (CHD) and has
been associated with arrhythmias, decreased functional status, and adverse ventricular …

Current understanding of the pathophysiology of myocardial fibrosis and its quantitative assessment in heart failure

T Liu, D Song, J Dong, P Zhu, J Liu, W Liu, X Ma… - Frontiers in …, 2017 - frontiersin.org
Myocardial fibrosis is an important part of cardiac remodeling that leads to heart failure and
death. Myocardial fibrosis results from increased myofibroblast activity and excessive …

The pathogenesis of cardiac fibrosis: a review of recent progress

K Maruyama, K Imanaka-Yoshida - International journal of molecular …, 2022 - mdpi.com
Fibrosis is defined as the excessive deposition of extracellular matrix (ECM) proteins in the
interstitium. It is an essential pathological response to chronic inflammation. ECM protein …

[HTML][HTML] Cardiac fibrosis: new insights into the pathogenesis

ZG Ma, YP Yuan, HM Wu, X Zhang… - International journal of …, 2018 - ncbi.nlm.nih.gov
Cardiac fibrosis is defined as the imbalance of extracellular matrix (ECM) production and
degradation, thus contributing to cardiac dysfunction in many cardiac pathophysiologic …

Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities

NG Frangogiannis - Molecular aspects of medicine, 2019 - Elsevier
Cardiac fibrosis is a common pathophysiologic companion of most myocardial diseases,
and is associated with systolic and diastolic dysfunction, arrhythmogenesis, and adverse …