Emerging studies have revealed new roles for the neural extracellular matrix in
neuropathologies. The structure of this matrix is unusual and uniquely enriched in …

Chondroitin sulfate (CS) carrying proteoglycans (PGs) are widely expressed in the nervous
system, and there is increasing evidence that they regulate developmental mechanisms like …

Aggrecan family proteoglycans, phosphacan/RPTPζ/β, and neuroglycan C (NGC) are the
major classes of chondroitin sulfate proteoglycan in the developing mammalian brain. A …

Proteoglycans are diverse, complex extracellular/cell surface macromolecules composed of
a central core protein with covalently linked glycosaminoglycan (GAG) chains; both of these …

Proteoglycan is a family of glycoproteins which carry covalently‐linked glycosaminoglycan
chains, such as chondroitin sulfate and heparan sulfate. Proteoglycans are believed to play …

The basic concept, that specialized extracellular matrices rich in hyaluronan, chondroitin
sulfate proteoglycans (aggrecan, versican, neurocan, brevican, phosphacan), link proteins …

Lecticans are a family of chondroitin sulfate proteoglycans, encompassing aggrecan,
versican, neurocan and brevican. These proteoglycans are characterized by the presence of …

The differentiation and morphogenesis of neural tissues involves a diversity of interactions
between neural cells and their environment. Many potentially important interactions occur …

Introduction 3. CS proteoglycans and biosynthesis of CS 3.1. Structure of CS proteoglycans
3.2. Biosynthesis and structure of CS 4. Functional significance of structural variation of CS …

The orderly development of the nervous system is characterized by phases of cell
proliferation and differentiation, neural migration, axonal outgrowth and synapse formation …