Chondroitin sulfate proteoglycans (CS-PGs) expressed by reactive astrocytes may
contribute to the axon growth-inhibitory environment of the injured CNS. The specific …

When embryonic thalamic neurons are plated onto living slices of mouse forebrain, cell
attachment and neurite outgrowth on different layers of the developing cerebral cortex vary …

Chondroitin sulfate proteoglycans (CSPGs) consist of a core protein and glycosaminoglycan
(GAG) chains. There is enormous structural diversity among CSPGs due to variation in the …

The current dogma in neural regeneration research implies that chondroitin sulfate
proteoglycans (CSPGs) inhibit plasticity and regeneration in the adult central nervous …

Chondroitin sulfate proteoglycans (CSPGs) are a family of extracellular matrix molecules
with various functions in regulating tissue morphogenesis, cell division, and axon guidance …

Proteoglycans are complex molecules composed of long, unbranched sugar chains
attached to a protein core. In the mammalian central nervous system, they are a major …

The central nervous system (CNS) develops from the neural tube, a hollow structure filled
with embryonic cerebrospinal fluid (eCSF) and surrounded by neuroepithelial cells. Several …

Neocortex, a distinct six-layered neural structure, is one of the most exquisite nerve tissues
in the human body. Proper assembly of neocortex requires precise regulation of neuronal …

Chondroitin sulfate (CS) proteoglycans bind with various proteins through CS chains in a CS
structure-dependent manner, in which oversulfated structures, such as iB (IdoA (2-O-sulfate) …

Using immunocytochemistry, we have compared the distribution of neurocan and
phosphacan in the developing central nervous system. At embryonic day 13 (E13) …