Chemical compositions responsible for inflammation and tissue damage in the mouse lung by coarse and fine particulate samples from contrasting air pollution in …
MS Happo, MR Hirvonen, AI Hälinen, PI Jalava… - Inhalation …, 2008 - Taylor & Francis
Inflammation is regarded as an important mechanism in mortality and morbidity associated
with exposures of cardiorespiratory patients to urban air particulate matter. We investigated …
with exposures of cardiorespiratory patients to urban air particulate matter. We investigated …
Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line
PI Jalava, MR Hirvonen, M Sillanpää… - Inhalation …, 2009 - Taylor & Francis
Epidemiological studies show heterogeneities in the particulate pollution-related exposure–
effect relationships among cardiorespiratory patients, but the connection to chemical …
effect relationships among cardiorespiratory patients, but the connection to chemical …
Inflammation and tissue damage in mouse lung by single and repeated dosing of urban air coarse and fine particles collected from six European cities
MS Happo, RO Salonen, AI Hälinen, PI Jalava… - Inhalation …, 2010 - Taylor & Francis
The authors have previously demonstrated heterogeneities in the inflammatory activities of
urban air fine (PM2. 5–0.2) and coarse (PM10–2.5) particulate samples collected from six …
urban air fine (PM2. 5–0.2) and coarse (PM10–2.5) particulate samples collected from six …
Dose and time dependency of inflammatory responses in the mouse lung to urban air coarse, fine, and ultrafine particles from six European cities
MS Happo, RO Salonen, AI Hälinen, PI Jalava… - Inhalation …, 2007 - Taylor & Francis
We investigated the dose and time dependency of inflammatory and cytotoxic responses to
size-segregated urban air particulate samples in the mouse lung. Coarse (PM10− 2.5), fine …
size-segregated urban air particulate samples in the mouse lung. Coarse (PM10− 2.5), fine …
Seasonal variation in chemical composition of size-segregated urban air particles and the inflammatory activity in the mouse lung
MS Happo, MR Hirvonen, AI Hälinen, PI Jalava… - Inhalation …, 2010 - Taylor & Francis
We investigated the seasonal variations in the chemical composition and in vivo
inflammatory activity of urban air particulate samples in four size ranges (PM10–2.5, PM2. 5 …
inflammatory activity of urban air particulate samples in four size ranges (PM10–2.5, PM2. 5 …
Inflammatory effects of coarse and fine particulate matter in relation to chemical and biological constituents
RPF Schins, JH Lightbody, PJA Borm, T Shi… - Toxicology and applied …, 2004 - Elsevier
There is conflicting evidence in the literature as to the predominant mechanism and also the
compositional element (s) that drives the pulmonary inflammatory response of ambient …
compositional element (s) that drives the pulmonary inflammatory response of ambient …
Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season
RB Hetland, FR Cassee, M Låg, M Refsnes… - Particle and fibre …, 2005 - Springer
Background Several studies have demonstrated an association between exposure to
ambient particulate matter (PM) and respiratory and cardiovascular diseases. Inflammation …
ambient particulate matter (PM) and respiratory and cardiovascular diseases. Inflammation …
Inhalation of concentrated particulate matter produces pulmonary inflammation and systemic biological effects in compromised rats
FR Cassee, AJF Boere, PHB Fokkens… - Journal of Toxicology …, 2005 - Taylor & Francis
Although significant progress has been made over the past few years, there is still debate on
the causal fractions that are responsible for particulate matter (PM)-associated adverse …
the causal fractions that are responsible for particulate matter (PM)-associated adverse …
Toxicity of coarse and fine particulate matter from sites with contrasting traffic profiles
ME Gerlofs-Nijland, JAMA Dormans… - Inhalation …, 2007 - Taylor & Francis
Residence in urban areas with much traffic has been associated with various negative
health effects. However, the contribution of traffic emissions to these adverse health effects …
health effects. However, the contribution of traffic emissions to these adverse health effects …
Determinants of the proinflammatory action of ambient particulate matter in immortalized murine macrophages
C Guastadisegni, FJ Kelly, FR Cassee… - Environmental …, 2010 - ehp.niehs.nih.gov
Background Proximity to traffic-related pollution has been associated with poor respiratory
health in adults and children. Objectives We wished to test the hypothesis that particulate …
health in adults and children. Objectives We wished to test the hypothesis that particulate …
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