The dual functions of YAP-1 to promote and inhibit cell growth in human malignancy
H Wang, YC Du, X Zhou, H Liu, SC Tang - Cancer and Metastasis Reviews, 2014 - Springer
The major functions of Hippo (Hpo) signaling pathway are to control cell growth,
proliferation, and apoptosis. As its important downstream player, yes-associated protein …
proliferation, and apoptosis. As its important downstream player, yes-associated protein …
[HTML][HTML] The prognostic value of YAP1 on clinical outcomes in human cancers
Y Wu, Y Hou, P Xu, Y Deng, K Liu, M Wang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Background: As an important downstream factor in the Hippo pathway, yes-associated
protein 1 (YAP1) has been detected to be elevated in various cancers and demonstrated to …
protein 1 (YAP1) has been detected to be elevated in various cancers and demonstrated to …
[HTML][HTML] Yes-associated protein expression is correlated to the differentiation of prostate adenocarcinoma
Background Yes-associated protein (YAP) in the Hippo signaling pathway is a growth
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …
Role of Yes-associated protein in cancer: An update
R Abylkassov, Y Xie - Oncology letters, 2016 - spandidos-publications.com
Yes-associated protein (YAP) is an oncoprotein located in the cytoplasm in an inactive form,
and when activated, it translocates to the nucleus and activates the transcription of genes …
and when activated, it translocates to the nucleus and activates the transcription of genes …
Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells
CH Diep, KM Zucker, G Hostetter, A Watanabe, C Hu… - PloS one, 2012 - journals.plos.org
Background The Hippo pathway regulates organ size by inhibiting cell proliferation and
promoting cell apoptosis upon its activation. The Yes Associated Protein 1 (YAP1) is a …
promoting cell apoptosis upon its activation. The Yes Associated Protein 1 (YAP1) is a …
YAP1 is involved in tumorigenic properties of prostate cancer cells
Abstract The Yes Associated Protein 1 (YAP1) is a transcriptional cofactor negatively
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
YAP 1 overexpression is associated with poor prognosis of breast cancer patients and induces breast cancer cell growth by inhibiting PTEN
L Guo, Y Chen, J Luo, J Zheng, G Shao - FEBS open bio, 2019 - Wiley Online Library
YES‐associated protein 1 (YAP 1) plays a key role as a transcriptional coactivator in the
Hippo tumor suppressor pathway. YAP 1 is overexpressed in a variety of cancers and is …
Hippo tumor suppressor pathway. YAP 1 is overexpressed in a variety of cancers and is …
YAP promotes the proliferation and migration of colorectal cancer cells through the Glut3/AMPK signaling pathway
L Jiang, J Zhang, Q Xu, B Wang, Y Yao… - Oncology …, 2021 - spandidos-publications.com
Abstract Yes‑associated protein (YAP), as a major downstream effector in the Hippo
signaling pathway, is considered as an oncogene in cancer. The present study aimed to …
signaling pathway, is considered as an oncogene in cancer. The present study aimed to …
[HTML][HTML] Effect of YAP inhibition on human leukemia HL-60 cells
M Chen, J Wang, SF Yao, Y Zhao, L Liu… - … Journal of Medical …, 2017 - ncbi.nlm.nih.gov
Background: Yes-associated protein (YAP), the nuclear effector of the Hippo pathway, is a
candidate oncoprotein and participates in the progression of various malignancies …
candidate oncoprotein and participates in the progression of various malignancies …
YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis
JJ Cao, XM Zhao, DL Wang, KH Chen… - Oncology …, 2014 - spandidos-publications.com
Yes-associated protein (YAP) has been reported to be an oncogene in a number of
malignancies. It constitutes an important regulatory mechanism for the Hippo pathway, a key …
malignancies. It constitutes an important regulatory mechanism for the Hippo pathway, a key …