Drug Repurposing: Uncovering New Uses for Existing Medications
S Showbharnikhaa, MKV MK - Journal of Pharma Insights and Research, 2023 - jopir.in
Drug repurposing, also known as drug repositioning or reprofiling, refers to the process of
identifying new therapeutic applications for existing drugs that were originally intended for …
identifying new therapeutic applications for existing drugs that were originally intended for …
Drug repurposing for cancer therapy, easier said than done
A Gonzalez-Fierro, A Dueñas-González - Seminars in cancer biology, 2021 - Elsevier
Drug repurposing for cancer therapy is currently a hot topic of research. Theoretically, in
contrast to the known hurdles of developing new molecular entities, the approach of …
contrast to the known hurdles of developing new molecular entities, the approach of …
Potential repurposing of oncology drugs for the treatment of Alzheimer's disease
W Araki - BMC medicine, 2013 - Springer
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia,
affecting about 30 million people worldwide. Despite recent advances in understanding its …
affecting about 30 million people worldwide. Despite recent advances in understanding its …
The drug repurposing landscape from 2012 to 2017: evolution, challenges, and possible solutions
P Polamreddy, N Gattu - Drug Discovery Today, 2019 - Elsevier
Highlights•Drug repurposing gained momentum in the recent past.•Drug repurposing is a
promising strategy for rare disease drug discovery.•Drug repurposing resulted in fruitful …
promising strategy for rare disease drug discovery.•Drug repurposing resulted in fruitful …
Repurposing drugs in oncology: From candidate selection to clinical adoption
P Pantziarka, C Verbaanderd, I Huys, G Bouche… - Seminars in Cancer …, 2021 - Elsevier
Drug repurposing is a strategy that aims to develop novel cancer treatments through the
reuse of existing medicines developed in other disease areas. Such a strategy includes the …
reuse of existing medicines developed in other disease areas. Such a strategy includes the …
[HTML][HTML] Drug repurposing: An effective strategy to accelerate contemporary drug discovery
P Zhan, B Yu, L Ouyang - Drug discovery today, 2022 - ncbi.nlm.nih.gov
Because of the high risk, substantial cost and slow pace of new drug discovery and
development, drug repurposing (also called repositioning, redirecting, reprofiling) is …
development, drug repurposing (also called repositioning, redirecting, reprofiling) is …
Repackaging FDA-approved drugs for degenerative diseases: promises and challenges
JL Cummings, K Zhong - Expert Review of Clinical Pharmacology, 2014 - Taylor & Francis
Repurposing refers to the therapeutic use of a drug or drug candidate for a disease other
than that for which it was originally intended. Repurposing is attractive as a drug …
than that for which it was originally intended. Repurposing is attractive as a drug …
Drug repurposing: far beyond new targets for old drugs
Repurposing drugs requires finding novel therapeutic indications compared to the ones for
which they were already approved. This is an increasingly utilized strategy for finding novel …
which they were already approved. This is an increasingly utilized strategy for finding novel …
Drug repositioning in sarcomas and other rare tumors
The exploration and identification of new anti-cancer therapeutic indications for an approved
drug already in use, or for a drug that was shelved for non-safety reasons in early clinical …
drug already in use, or for a drug that was shelved for non-safety reasons in early clinical …
[HTML][HTML] Inventing new therapies without reinventing the wheel: the power of drug repurposing
A Papapetropoulos, C Szabo - British journal of pharmacology, 2018 - ncbi.nlm.nih.gov
Current drug development strategies devote extensive effort to identifying the molecular
mechanism of action of new drug candidates. Often, if more than one unrelated enzyme or …
mechanism of action of new drug candidates. Often, if more than one unrelated enzyme or …