Background: The immune modulating molecules cyclooxygenase-2 (COX-2), transforming
growth factor-β (TGF-β) and interleukin-10 (IL-10) have regulatory roles in cancer …

Purpose: Chronic inflammation is linked to the development of cancer in several organs,
including the prostate. Up-regulated cyclooxygenase-2 (COX-2) may play a role in …

Lack of reliable prognostic markers hinders accurate prediction of disease progression in
prostate cancer. The inducible proinflammatory enzyme cyclooxygenase‐2 (COX‐2) is …

Epidemiological studies provided the first evidence that COX may be involved in the
pathogenesis of cancer. In the process of carcinogenesis and in the route of intracellular …

Background COX-2 is overexpressed in some cancers, including prostate cancer; however,
little is known about the effect of COX-2 overexpression on outcome in radiation-treated …

Abstract Cyclooxygenase (COX)-2 expression is elevated in some malignancies; however,
information is scarce regarding COX-2 contributions to the development of prostate cancer …

Background Chronic inflammation has been suggested to be linked to the development and
progression of prostate cancer. An inflammatory microenvironment may support the …

Abstract BACKGROUND Cyclooxygenase (COX)‐2, an inducible isoform of COX, has been
observed to be expressed in prostate cancer. Several studies have reported that COX‐2 …

Objectives: To determine whether COX-2, bcl-2 and neoangiogenesis are related to human
prostate cancer relapse after definitive surgical treatment and progression toward androgen …

Elevated expression of cyclo-oxygenase (COX)-2 has been found in several human
cancers, including prostate adenocarcinoma. To evaluate the potential prognostic role of …