Levels of natural IgM antibodies against phosphorylcholine in healthy individuals and in patients undergoing isolated limb perfusion

ND Padilla, C Ciurana, J van Oers, AC Ogilvie… - Journal of …, 2004 - Elsevier
Natural IgM antibodies against phosphorylcholine (anti-Pc IgM) resemble C-reactive protein
(CRP) regarding specificity and have gained increasing attention because of their supposed …

Natural antibodies against phosphorylcholine in cardiovascular disease

U De Faire, J Frostegård - Annals of the New York Academy of …, 2009 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease characterized by the presence of activated
immune‐competent cells in the lesions, producing mainly proinflammatory cytokines …

Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases

MR de Vries, MM Ewing, RCM de Jong… - Journal of Internal …, 2021 - Wiley Online Library
Background Phosphorylcholine (PC) is an important pro‐inflammatory damage‐associated
molecular pattern. Previous data have shown that natural IgM anti‐PC protects against …

Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease

J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …

[HTML][HTML] Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases

J Frostegård - Metabolites, 2023 - mdpi.com
Atherosclerosis and its main consequence, cardiovascular disease (CVD) are nowadays
regarded as chronic inflammatory disease conditions, and CVD is the main cause of death …

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
Introduction Chronic inflammatory diseases include cardiovascular disease (CVD),
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …

Immunoglobulin G1 antibodies against phosphorylcholine are associated with protection in systemic lupus erythematosus and atherosclerosis: potential underlying …

D Thiagarajan, R Fiskesund, A Frostegård… - ACR open …, 2020 - Wiley Online Library
Objective Immunoglobulin M antibodies against phosphorylcholine (anti‐PC s) may be
protective in atherosclerosis, cardiovascular disease (CVD), and systemic lupus …

Natural antibodies against phosphorylcholine as potential protective factors in SLE

J Su, X Hua, H Concha, E Svenungsson… - …, 2008 - academic.oup.com
Objective. We have recently reported that natural antibodies against phosphorylcholine (anti-
PC) have atheroprotective properties. Here we compare anti-PC with other autoantibodies in …

Low levels of IgM antibodies against phosphorylcholine—a potential risk marker for ischemic stroke in men

BG Sjöberg, J Su, I Dahlbom, H Grönlund, M Wikström… - Atherosclerosis, 2009 - Elsevier
BACKGROUND: Natural antibodies specific for phosphorylcholine (anti-PC) have been
implicated as protective factors in atherosclerosis. We herein determined the relationship …

Long-term prognostic value of IgM antibodies against phosphorylcholine for adverse cardiovascular events in patients with stable coronary heart disease

A Imhof, W Koenig, A Jaensch, U Mons, H Brenner… - Atherosclerosis, 2015 - Elsevier
Abstract Background Low concentrations of IgM-phosphorylcholine autoantibodies (IgM-anti-
PC) have been shown to be associated with increased risk of incident cardiovascular …