The impact of depressive symptoms in early Parkinson disease

B Ravina, R Camicioli, PG Como, L Marsh, J Jankovic… - Neurology, 2007 - AAN Enterprises
Background: Depressive disorders may affect up to 50% of patients with Parkinson disease
(PD) and are associated with increased disability and reduced quality of life. No previous …

Course of psychiatric symptoms and global cognition in early Parkinson disease

P de la Riva, K Smith, SX Xie, D Weintraub - Neurology, 2014 - AAN Enterprises
Objective: To evaluate the course and predictors of neuropsychiatric symptoms (NPS) and
cognition in patients with de novo Parkinson disease (PD). Methods: Cross-sectional study …

Depression in Parkinson's disease: conceptual issues and clinical challenges

AFG Leentjens - Journal of geriatric psychiatry and …, 2004 - journals.sagepub.com
Background: Depression frequently accompanies Parkinson's disease (PD) and may have a
negative impact on activities of daily living, cognitive performance, and quality of life …

Occurrence risk and structure of depression in Parkinson disease with and without dementia: results from the GEPAD Study

O Riedel, I Heuser, J Klotsche… - Journal of Geriatric …, 2010 - journals.sagepub.com
Background: This study examined the age-and gender-specific risk of depression in
demented and non-demented participants, its symptom structure, and associated clinical …

A comparison of nine scales to detect depression in Parkinson disease: which scale to use?

JR Williams, ES Hirsch, K Anderson, AL Bush… - Neurology, 2012 - AAN Enterprises
Objective: The Methods of Optimal Depression Detection in Parkinson's Disease (MOOD-
PD) study compared the psychometric properties of 9 depression scales to provide guidance …

Depression in patients with early versus late onset of Parkinson's disease

SE Starkstein, ML Berthier, PL Bolduc, TJ Preziosi… - Neurology, 1989 - AAN Enterprises
We examined correlates of depression in patients whose onset of Parkinson's disease (PD)
began before age 55 (early-onset group) compared with patients whose onset was after age …

The longitudinal impact of depression on disability in Parkinson disease

GM Pontone, CC Bakker, S Chen, Z Mari… - … journal of geriatric …, 2016 - Wiley Online Library
Objective Depression in Parkinson disease (PD) is a common problem that worsens quality
of life and causes disability. However, little is known about the longitudinal impact of …

Factors associated with depression in Parkinson's disease

NNW Dissanayaka, A Sellbach, PA Silburn… - Journal of affective …, 2011 - Elsevier
BACKGROUND: Depression is common in Parkinson's disease (PD) and contributes
significantly to a reduced quality of life in PD patients. The determinants of depression in PD …

Depression in Parkinson's disease: impediments to recognition and treatment options.

W Poewe, E Luginger - Neurology, 1999 - europepmc.org
By some estimates, nearly half of patients with PD also suffer depression. Because features
of PD frequently overlap with typical manifestations of major affective disorder (or mild …

Depression in Parkinson's disease: clinical correlates and outcome

A Rojo, M Aguilar, MT Garolera, E Cubo, I Navas… - Parkinsonism & related …, 2003 - Elsevier
Depression has been shown to be more common in Parkinson's disease (PD) than in other
chronic and disabling disorders. Neurochemical and functional disturbances are important …