Altered expression of piRNAs and their relation with clinicopathologic features of breast cancer

G Huang, H Hu, X Xue, S Shen, E Gao, G Guo… - Clinical and …, 2013 - Springer
Abstract Introduction PIWI interacting RNAs (piRNAs) are endogenous regulatory non-
coding RNAs which are generally expressed in the germline across animal species. The …

PIWI-interacting RNAs: new biomarkers for diagnosis and treatment of breast cancer

P Maleki Dana, MA Mansournia, SM Mirhashemi - Cell & Bioscience, 2020 - Springer
Cancer is one of the most important reasons of mortality in the world. However, there are
several therapeutic platforms to treat patients who suffering from cancer common treatments …

[HTML][HTML] Piwi-interacting RNAs and PIWI genes as novel prognostic markers for breast cancer

P Krishnan, S Ghosh, K Graham, JR Mackey… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract Piwi-interacting RNAs (piRNAs), whose role in germline maintenance has been
established, are now also being classified as post-transcriptional regulators of gene …

PIWI-interacting RNA 021285 is involved in breast tumorigenesis possibly by remodeling the cancer epigenome

A Fu, DI Jacobs, AE Hoffman, T Zheng, Y Zhu - Carcinogenesis, 2015 - academic.oup.com
Abstract Although PIWI-interacting RNAs (piRNAs) account for the largest class of the small
non-coding RNA superfamily, virtually nothing is known of their function in human …

Estrogen and androgen hormone levels modulate the expression of PIWI interacting RNA in prostate and breast cancer

Ç Öner, D Turgut Coşan, E Çolak - PLoS One, 2016 - journals.plos.org
PIWI interacting RNAs (piRNAs), a member of non-coding RNA, originate from intergenic
repetitive regions of the genome. piRNA expressions increase in various cancers and it is …

Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

VD Martinez, EA Vucic, KL Thu, R Hubaux… - Scientific reports, 2015 - nature.com
Abstract Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline
cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues …

piRNAs: biogenesis and their potential roles in cancer

B Guo, D Li, L Du, X Zhu - Cancer and Metastasis Reviews, 2020 - Springer
With the length of about 26–31 nt, PIWI-interacting RNA (piRNA) is a small non-coding RNA
(ncRNA) that interacts with PIWI proteins to form the piRNA silencing complex (piRISC). PIWI …

The emerging role of the piRNA/piwi complex in cancer

Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …

The emerging roles of PIWI-interacting RNA in human cancers

Y Yu, J Xiao, SS Hann - Cancer Management and Research, 2019 - Taylor & Francis
PIWI-interacting RNAs (piRNAs) are a type of non-coding RNAs that interact with PIWI
proteins, which are members of the argonaute family. Originally described in the germline …

Identification of novel piRNAs in bladder cancer

H Chu, G Hui, L Yuan, D Shi, Y Wang, M Du, D Zhong… - Cancer letters, 2015 - Elsevier
PIWI-interacting RNAs (piRNAs) are a newly identified class of small non-coding RNAs that
can play important roles in germline development and carcinogenesis. In this study, piRNA …