[HTML][HTML] Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci
L Mikkola, S Holopainen, T Pessa-Morikawa… - BMC genomics, 2019 - Springer
Background Hip dysplasia and osteoarthritis continue to be prevalent problems in veterinary
and human medicine. Canine hip dysplasia is particularly problematic as it massively affects …
and human medicine. Canine hip dysplasia is particularly problematic as it massively affects …
[HTML][HTML] An across-breed validation study of 46 genetic markers in canine hip dysplasia
L Mikkola, K Kyöstilä, J Donner, AK Lappalainen… - BMC genomics, 2021 - Springer
Background Canine hip dysplasia (CHD) is a common disease, with a complex genetic
background. Dogs with severe CHD sometimes also suffer from osteoarthritis (OA), an …
background. Dogs with severe CHD sometimes also suffer from osteoarthritis (OA), an …
The long (and winding) road to gene discovery for canine hip dysplasia
L Zhu, Z Zhang, S Friedenberg, SW Jung… - The Veterinary …, 2009 - Elsevier
Hip dysplasia is a common inherited trait of dogs that results in secondary osteoarthritis. In
this article the methods used to uncover the mutations contributing to this condition are …
this article the methods used to uncover the mutations contributing to this condition are …
[HTML][HTML] Differential genetic regulation of canine hip dysplasia and osteoarthritis
Background Canine hip dysplasia (HD) is a common polygenic trait characterized by hip
malformation that results in osteoarthritis (OA). The condition in dogs is very similar to …
malformation that results in osteoarthritis (OA). The condition in dogs is very similar to …
Emerging insights into the genetic basis of canine hip dysplasia
Canine hip dysplasia (CHD) is the most common inherited polygenic orthopedic trait in dogs
with the phenotype influenced also by environmental factors. This trait was described in the …
with the phenotype influenced also by environmental factors. This trait was described in the …
[HTML][HTML] Canine hip dysplasia is predictable by genotyping
OBJECTIVE: To establish a predictive method using whole genome genotyping for early
intervention in canine hip dysplasia (CHD) risk management, for the prevention of the …
intervention in canine hip dysplasia (CHD) risk management, for the prevention of the …
[HTML][HTML] Identification and validation of quantitative trait loci (QTL) for canine hip dysplasia (CHD) in German shepherd dogs
L Fels, O Distl - PloS one, 2014 - journals.plos.org
Canine hip dysplasia (CHD) is the most common hereditary skeletal disorder in dogs. To
identify common alleles associated with CHD, we genotyped 96 German Shepherd Dogs …
identify common alleles associated with CHD, we genotyped 96 German Shepherd Dogs …
[HTML][HTML] Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period
A Baldinger, JP Genevois, P Moissonnier… - Plos one, 2020 - journals.plos.org
Canine hip dysplasia (HD) is a complex developmental disease of the coxo-femoral joint
and is one of the most common orthopedic conditions in dogs. Due to the genetic …
and is one of the most common orthopedic conditions in dogs. Due to the genetic …
Mapping quantitative trait loci for canine hip dysplasia in German Shepherd dogs
Y Marschall, O Distl - Mammalian Genome, 2007 - Springer
Canine hip dysplasia (CHD) is a common hereditary developmental disease of the
coxofemoral joints. CHD is characterized by subluxation of the femoral head and …
coxofemoral joints. CHD is characterized by subluxation of the femoral head and …
[HTML][HTML] A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches
N Bartolomé, S Segarra, M Artieda, O Francino… - PLoS …, 2015 - journals.plos.org
Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in
dogs worldwide. Unfortunately, the success of eradication programs against this disease …
dogs worldwide. Unfortunately, the success of eradication programs against this disease …