[HTML][HTML] Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci

L Mikkola, S Holopainen, T Pessa-Morikawa… - BMC genomics, 2019 - Springer
Background Hip dysplasia and osteoarthritis continue to be prevalent problems in veterinary
and human medicine. Canine hip dysplasia is particularly problematic as it massively affects …

[HTML][HTML] An across-breed validation study of 46 genetic markers in canine hip dysplasia

L Mikkola, K Kyöstilä, J Donner, AK Lappalainen… - BMC genomics, 2021 - Springer
Background Canine hip dysplasia (CHD) is a common disease, with a complex genetic
background. Dogs with severe CHD sometimes also suffer from osteoarthritis (OA), an …

The long (and winding) road to gene discovery for canine hip dysplasia

L Zhu, Z Zhang, S Friedenberg, SW Jung… - The Veterinary …, 2009 - Elsevier
Hip dysplasia is a common inherited trait of dogs that results in secondary osteoarthritis. In
this article the methods used to uncover the mutations contributing to this condition are …

[HTML][HTML] Differential genetic regulation of canine hip dysplasia and osteoarthritis

Z Zhou, X Sheng, Z Zhang, K Zhao, L Zhu, G Guo… - PloS one, 2010 - journals.plos.org
Background Canine hip dysplasia (HD) is a common polygenic trait characterized by hip
malformation that results in osteoarthritis (OA). The condition in dogs is very similar to …

Emerging insights into the genetic basis of canine hip dysplasia

M Ginja, AR Gaspar, C Ginja - Veterinary Medicine: Research and …, 2015 - Taylor & Francis
Canine hip dysplasia (CHD) is the most common inherited polygenic orthopedic trait in dogs
with the phenotype influenced also by environmental factors. This trait was described in the …

[HTML][HTML] Canine hip dysplasia is predictable by genotyping

G Guo, Z Zhou, Y Wang, K Zhao, L Zhu, G Lust… - Osteoarthritis and …, 2011 - Elsevier
OBJECTIVE: To establish a predictive method using whole genome genotyping for early
intervention in canine hip dysplasia (CHD) risk management, for the prevention of the …

[HTML][HTML] Identification and validation of quantitative trait loci (QTL) for canine hip dysplasia (CHD) in German shepherd dogs

L Fels, O Distl - PloS one, 2014 - journals.plos.org
Canine hip dysplasia (CHD) is the most common hereditary skeletal disorder in dogs. To
identify common alleles associated with CHD, we genotyped 96 German Shepherd Dogs …

[HTML][HTML] Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period

A Baldinger, JP Genevois, P Moissonnier… - Plos one, 2020 - journals.plos.org
Canine hip dysplasia (HD) is a complex developmental disease of the coxo-femoral joint
and is one of the most common orthopedic conditions in dogs. Due to the genetic …

Mapping quantitative trait loci for canine hip dysplasia in German Shepherd dogs

Y Marschall, O Distl - Mammalian Genome, 2007 - Springer
Canine hip dysplasia (CHD) is a common hereditary developmental disease of the
coxofemoral joints. CHD is characterized by subluxation of the femoral head and …

[HTML][HTML] A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches

N Bartolomé, S Segarra, M Artieda, O Francino… - PLoS …, 2015 - journals.plos.org
Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in
dogs worldwide. Unfortunately, the success of eradication programs against this disease …