Over the 75‐year lifetime of the British Pharmacological Society there has been an
enormous expansion in our understanding of how opioid drugs act on the nervous system …

This paper is the eleventh installment in our annual review of the research during the past
year involving the endogenous opiate system. It is concerned with nonanalgesic and …

Before the discovery of the endogenous opioid system in the 1970s, opioids were
understood only through the lens of opioid drug effects. Opium produced sleep, pain relief …

This paper is the tenth installment of our annual review of the research during the past year
involving the endogenous opiate system. It covers the nonanalgesia and behavioral studies …

This paper is the eighth installment of our annual review of research involving the
endogenous opiate peptides. It is restricted to the non-analgesic and behavioral studies of …

The opioid system consists of three receptors, mu, delta, and kappa, which are activated by
endogenous opioid peptides processed from three protein precursors, proopiomelanocortin …

This paper is the fifteenth installment of our annual review of research concerning the opiate
system. It includes papers published during 1992 involving the behavioral, nonanalgesic …

It has been estimated that more than 80% of alcoholics are also nicotine dependent and
that, vice versa, the rate of alcoholism is substantially increased by a factor of 4–10 in the …

Endogenous opioid peptides and opiates like morphine produce their pharmacological
effects through the membrane bound opioid receptors. These receptors belong to a …

In this minireview, I have described the primary structures of the various groups of naturally
occurring peptides with activity in opiate bioassay systems, and the structural and …