Objective: This review summarizes recent findings on the epigenetics of Alzheimer's disease
(AD) and provides therapeutic strategies for AD. Methods: We searched the following …

Research over the years has shown that causes of Alzheimer's disease are not well
understood, but over the past years, the involvement of epigenetic mechanisms in the …

Alzheimer's disease (AD) is a well-known neurodegenerative disorder that imposes a great
burden on the world. The mechanisms of AD are not yet fully understood. Current insight into …

Alzheimer's disease is a progressive neurodegenerative disorder, affecting 50 million
people worldwide, for which there is no cure, or effective treatment. Individuals suffering from …

The advent of new technologies and analytic approaches is beginning to provide an
unprecedented look at features of the human genome that affect RNA expression. These …

Introduction DNA methylation is a key epigenetic mechanism in brain aging and Alzheimer's
disease (AD). The newly discovered 5-hydroxymethylcytosine mediates DNA demethylation …

Epigenetic alterations have been associated with several human diseases including
Alzheimer's disease (AD). AD is a complex neurodegenerative disease characterized by a …

The vast majority of Alzheimer's disease (AD) are late-onset forms (LOAD) likely due to the
interplay of environmental influences and individual genetic susceptibility. Epigenetic …

The observation that Alzheimer's disease (AD) patients with similar and even identical
genetic backgrounds often present with heterogeneous pathologies has prompted the …

Epigenetic regulation, such as DNA methylation and histone modification, is implicated in
the aberrant changes in gene expression that occur during the progression of …