[PDF][PDF] Efficacy of brain radiotherapy plus EGFR-TKI for EGFR-mutated NSCLC patients who develop brain metastasis

W Wang, Z Song, Y Zhang - Archives of Medical Science, 2018 - termedia.pl
Results In 49 symptomatic BM patients, the median OS of the stereotactic radiosurgery
(SRS)-treated group was longer than in the whole brain radiotherapy (WBRT) group (37.7 …

[HTML][HTML] EGFR-TKI plus brain radiotherapy versus EGFR-TKI alone in the management of EGFR-mutated NSCLC patients with brain metastases

K Dong, W Liang, S Zhao, M Guo, Q He… - Translational Lung …, 2019 - ncbi.nlm.nih.gov
Background It has been confirmed that epidermal growth factor receptor-tyrosine kinase
inhibitors (EGFR-TKIs) presented better efficacy than brain radiotherapy (brain RT) in the …

[HTML][HTML] Efficacy and safety of radiotherapy plus EGFR-TKIs in NSCLC patients with brain metastases: a meta-analysis of published data

X Wang, Y Xu, W Tang, L Liu - Translational oncology, 2018 - Elsevier
Background: The role of radiotherapy (RT) combined with epidermal growth factor receptor
tyrosine kinase inhibitors (EGFR-TKIs) in non-small cell lung cancer (NSCLC) patients with …

Improved survival and intracranial tumor control of EGFR-mutated NSCLC patients with newly developed brain metastases following stereotactic radiosurgery and …

AS Kuan, CL Chiang, HM Wu, HC Yang… - Journal of Neuro …, 2023 - Springer
Purpose To examine the differential effects of SRS and TKI on EGFR-mutated NSCLC
patients with brain metastases (BMs) and outcomes following continuation of the same TKI …

[HTML][HTML] EGFR TKIs plus WBRT demonstrated no survival benefit other than that of TKIs alone in patients with NSCLC and EGFR mutation and brain metastases

T Jiang, C Su, X Li, C Zhao, F Zhou, S Ren… - Journal of Thoracic …, 2016 - Elsevier
Introduction Whether EGFR tyrosine kinase inhibitors (TKIs) plus whole brain radiation
therapy (WBRT) provide a better survival benefit than EGFR TKIs alone remains …

Therapeutic effect of first-line EGFR-TKIs combined with concurrent cranial radiotherapy on NSCLC patients with EGFR activating mutation and brain metastasis: a …

N An, H Wang, J Li, X Zhai, W Jing, W Jia… - OncoTargets and …, 2019 - Taylor & Francis
Purpose Non-small cell lung cancer (NSCLC) patients with EGFR mutation are suffering
from a high incidence of brain metastasis (BM). It is still controversial whether cranial …

Whole brain radiation therapy does not improve the overall survival of EGFR-mutant NSCLC patients with leptomeningeal metastasis

W Yan, Y Liu, J Li, A Han, L Kong, J Yu, H Zhu - Radiation Oncology, 2019 - Springer
Background Leptomeningeal metastasis (LM) is a devastating and terminal complication of
advanced non-small-cell lung cancer (NSCLC), especially in patients harboring epidermal …

Concurrent versus sequential whole brain radiotherapy and TKI in EGFR-mutated NSCLC patients with brain metastasis: a single institution retrospective analysis

H Chen, A Wu, H Tao, D Yang, Y Luo, S Li, Z Yang… - Medicine, 2018 - journals.lww.com
Concurrent versus sequential whole brain radiotherapy and TK... : Medicine Concurrent versus
sequential whole brain radiotherapy and TKI in EGFR-mutated NSCLC patients with brain …

Analysis of the benefit of sequential cranial radiotherapy in patients with EGFR mutant non-small cell lung cancer and brain metastasis

S Byeon, JS Ham, JM Sun, SH Lee, JS Ahn, K Park… - Medical Oncology, 2016 - Springer
Although cranial radiotherapy is considered the standard treatment for brain metastasis
(BM), EGFR tyrosine kinase inhibitors (TKIs) have shown promising activity in EGFR mutant …

Comparing the efficacy of concurrent EGFR-TKI and whole-brain radiotherapy vs EGFR-TKI alone as a first-line therapy for advanced EGFR-mutated non-small-cell …

ZY He, MF Li, JH Lin, D Lin, RJ Lin - Cancer management and …, 2019 - Taylor & Francis
Background Non-small-cell lung cancer (NSCLC) is a global public health problem, and
brain is a common metastatic site in advanced NSCLC. Currently, whole-brain radiotherapy …