Cardiovascular diseases, including atherosclerosis and the dreaded complication
myocardial infarction, represent the major cause of death in western countries. It is now …

In their role as small chemotactic cytokines, chemokines are crucial mediators and
regulators of leukocyte trafficking during immune surveillance and inflammation. Their …

Chemokines are newly discovered molecules that mediate the migration of leukocytes into
inflammed tissues and control the inflammatory reactions in various immune-mediated …

Introduction: Inflammation is a well-known powerful effector of atherosclerosis development.
Cell infiltration induces inflammatory signal increasing plaque formation as well as its …

Atherosclerosis is a chronic inflammatory disease that represents the primary cause of heart
disease and stroke. The recruitment of inflammatory cells in the intima is an essential step in …

Atherosclerotic cardiovascular disease is the leading cause of death worldwide. Despite
extraordinary advances in the understanding of the pathophysiology and the utilization of …

Chemokines are key mediators of inflammation. In pathological tissues, the main roles of
chemokines are to regulate leucocyte accumulation through the activation of oriented cell …

Atherosclerosis as the underlying mechanisms of myocardial infarction, stroke and
peripheral artery disease remains the major cause of morbidity and mortality in developed …

Chemokines and their receptors represent a potential target for immunotherapy in chronic
inflammation. They comprise a large family of cytokines with chemotactic activity, and their …

Current perspectives on the pathogenesis of atherosclerosis strongly support the
involvement of inflammatory mediators in the establishment and progression of …