In this study, we developed oral core–shell nanoparticles composed of curcumin
nanocrystals in the core and chitosan/alginate multilayers in the shell for inflammation …

Ulcerative colitis (UC) is an idiopathic inflammatory condition of colorectal regions. Existing
therapies for UC face grave lacunae including off-target and other harmful side effects …

An oral nanoparticle (NPs) encapsulated in chitosan/alginate hydrogel (CA-Gel) with dual-
sensitive in pH and reactive oxygen species (ROS) was developed to load curcumin (CUR) …

Orally targeted delivery of anti-inflammatory drugs to macrophages has attracted great
attention for minimizing the symptoms of ulcerative colitis (UC). In this investigation, we …

pH-Responsive nanotherapeutics were recently developed for the treatment of ulcerative
colitis (UC). However, they target the entire colon rather than the UC site, which leads to …

Oral colon-specific drug delivery is of great interest for ulcerative colitis (UC) therapy. Here,
an emulsion-solvent evaporation method was used to fabricate microparticles (MPs) with pH …

Inflammatory bowel disease (IBD) is an inflammatory condition with mucosal ulceration,
edema and hemorrhage of gastrointestinal tract. Curcumin has been shown to mitigate …

Although nano-systems can promote the cellular internalization, polymeric nanoparticles
(NPs) are easily to be destroyed or eliminated in the gastrointestinal tract, which leads to …

Ulcerative colitis (UC) is a chronic inflammatory illness affecting the colon and rectum, with
current treatment methods being unable to meet the clinical needs of ulcerative colitis …

Background Due to oral nano-delivery systems for the treatment of inflammatory bowel
disease (IBD) are often failed to accumulated to the colonic site and could not achieve …