IgH sequences in common variable immune deficiency reveal altered B cell development and selection
Common variable immune deficiency (CVID) is the most common symptomatic primary
immune deficiency, affecting~ 1 in 25,000 persons. These patients suffer from impaired …
immune deficiency, affecting~ 1 in 25,000 persons. These patients suffer from impaired …
Current genetic landscape in common variable immune deficiency
H Abolhassani, L Hammarström… - Blood, The Journal …, 2020 - ashpublications.org
Using whole-exome sequencing to examine the genetic causes of immune deficiency in 235
common variable immunodeficiency (CVID) patients seen in the United States (Mount Sinai …
common variable immunodeficiency (CVID) patients seen in the United States (Mount Sinai …
B-cell replication history and somatic hypermutation status identify distinct pathophysiologic backgrounds in common variable immunodeficiency
GJ Driessen, MC Van Zelm… - Blood, The Journal …, 2011 - ashpublications.org
Common variable immunodeficiency disorder (CVID) is the most prevalent form of primary
idiopathic hypogammaglobulinemia. Identification of genetic defects in CVID is hampered by …
idiopathic hypogammaglobulinemia. Identification of genetic defects in CVID is hampered by …
Perspectives on common variable immune deficiency
JH Park, ES Resnick… - Annals of the New …, 2011 - Wiley Online Library
Common variable immunodeficiency (CVID) is considered to be a collection of genetic
immune defects with complex inheritance patterns. While the main phenotype is loss of B …
immune defects with complex inheritance patterns. While the main phenotype is loss of B …
Identification of CVID patients with defects in immune repertoire formation or specification
PA Van Schouwenburg, H IJspeert… - Frontiers in …, 2018 - frontiersin.org
Common variable immune deficiency disorder (CVID) is the most clinically relevant cause of
antibody failure. It is a highly heterogeneous disease with different underlying etiologies …
antibody failure. It is a highly heterogeneous disease with different underlying etiologies …
[HTML][HTML] Accelerated loss of TCR repertoire diversity in common variable immunodeficiency
Although common variable immunodeficiency (CVID) has long been considered as a group
of primary Ab deficiencies, growing experimental data now suggest a global disruption of the …
of primary Ab deficiencies, growing experimental data now suggest a global disruption of the …
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses
Common variable immunodeficiency (CVID), the most prevalent symptomatic primary
immunodeficiency, displays impaired terminal B-cell differentiation and defective antibody …
immunodeficiency, displays impaired terminal B-cell differentiation and defective antibody …
B-cell defects in common variable immunodeficiency: BCR signaling, protein clustering and hardwired gene mutations
AAJM van de Ven, EB Compeer… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
Common variable immunodeficiency (CVID) is the most frequently diagnosed symptomatic
primary immunodeficiency. CVID develops as a consequence of absence or malfunction of …
primary immunodeficiency. CVID develops as a consequence of absence or malfunction of …
Members of the regulatory lymphocyte club in common variable immunodeficiency
S Gupta, Y Demirdag, AA Gupta - Frontiers in Immunology, 2022 - frontiersin.org
The role of CD4 T regulatory cells is well established in peripheral tolerance and the
pathogenesis of the murine model and human autoimmune diseases. CD4 T regulatory cells …
pathogenesis of the murine model and human autoimmune diseases. CD4 T regulatory cells …
Absence of memory B cells in patients with common variable immunodeficiency
K Agematsu, T Futatani, S Hokibara, N Kobayashi… - Clinical …, 2002 - Elsevier
The molecular basis of common variable immunodeficiency (CVID) is unknown. To assess
humoral immunity in CVID, we selected 24 patients with early or late onset of disease. X …
humoral immunity in CVID, we selected 24 patients with early or late onset of disease. X …