The amygdala is critical for opioid-mediated binge eating of fat

MJ Will, EB Franzblau, AE Kelley - Neuroreport, 2004 - journals.lww.com
Endogenous opioid peptides within the nucleus accumbens are thought to mediate the
hedonic aspects of food intake, particularly foods such as fat and sugar. In view of evidence …

Central amygdala opioid transmission is necessary for increased high-fat intake following 24-h food deprivation, but not following intra-accumbens opioid …

KE Parker, HW Johns, TG Floros, MJ Will - Behavioural brain research, 2014 - Elsevier
Previous research has demonstrated a dissociation of certain neural mediators that
contribute to the increased consumption of a high-fat diet that follows intra-accumbens (Acb) …

Nucleus accumbens μ-opioids regulate intake of a high-fat diet via activation of a distributed brain network

MJ Will, EB Franzblau, AE Kelley - Journal of Neuroscience, 2003 - Soc Neuroscience
Endogenous opioid peptides within the nucleus accumbens, a forebrain site critical for the
regulation of reward-related behavior, are believed to play an important role in the control of …

Endogenous opioids in the nucleus accumbens promote approach to high-fat food in the absence of caloric need

K Caref, SM Nicola - Elife, 2018 - elifesciences.org
When relatively sated, people (and rodents) are still easily tempted to consume calorie-
dense foods, particularly those containing fat and sugar. Consumption of such foods while …

Intake of high-fat food is selectively enhanced by muopioid receptor stimulation within the nucleus accumbens

M Zhang, BA Gosnell, AE Kelley - Journal of Pharmacology and …, 1998 - ASPET
The present study was designed to further investigate the nature of feeding induced by
opioid stimulation of the nucleus accumbens through an examination of the effects of intra …

Pharmacological characterization of high-fat feeding induced by opioid stimulation of the ventral striatum

MJ Will, WE Pratt, AE Kelley - Physiology & behavior, 2006 - Elsevier
Nucleus accumbens μ-opioid stimulation causes marked increases in the intake of highly
palatable foods, such as a high-fat diet. However, to date there has been little examination of …

Nucleus accumbens opioids regulate flavor-based preferences in food consumption

JD Woolley, BS Lee, HL Fields - Neuroscience, 2006 - Elsevier
Opioid signaling in the nucleus accumbens (NAcc) regulates feeding behavior, having
particularly strong effects on consumption of highly palatable foods. Since macronutrient …

μ-Opioid receptor stimulation in the nucleus accumbens elevates fatty tastant intake by increasing palatability and suppressing satiety signals

Y Katsuura, JA Heckmann… - American Journal of …, 2011 - journals.physiology.org
Infusion of a μ-opioid receptor (MOR) agonist into the nucleus accumbens (NAcc) drives
voracious food intake, an effect hypothesized to occur through increased tastant palatability …

Reversible suppression of food reward behavior by chronic mu-opioid receptor antagonism in the nucleus accumbens

AC Shin, PJ Pistell, CB Phifer, HR Berthoud - Neuroscience, 2010 - Elsevier
Overindulgence in easily available energy-dense palatable foods is thought to be an
important factor in the current obesity epidemic but the underlying neural mechanisms are …

Basolateral amygdala response to food cues in the absence of hunger is associated with weight gain susceptibility

X Sun, NB Kroemer, MG Veldhuizen… - Journal of …, 2015 - Soc Neuroscience
In rodents, food-predictive cues elicit eating in the absence of hunger (Weingarten, 1983).
This behavior is disrupted by the disconnection of amygdala pathways to the lateral …