Tumorigenesis or carcinogenesis is a multi-step process that is induced primarily by
carcinogens leading to the development of cancer. Extensive research in the last few years …

Chemoprevention has been shown to be an extremely promising approach to the prevention
of invasive cancer. Through the identification of chemopreventive agents that inhibit or …

This paper proposes a scientific basis and possible strategy for applying surrogate end
points in chemopreventive drug development. The potential surrogate end points for cancer …

The ultimate toxic effect of many natural environmental pollutants as well as synthetic
chemicals is the development of cancer, which next only to heart diseases, is the second …

Abstract In the NCI, Chemoprevention Branch drug development program, potential
chemopreventive agents are evaluated for efficacy against chemical carcinogen–induced …

Chemoprevention is a strategy used to block the development of cancers in human beings.
This emerging field has broad potential for influencing cancer incidence rates in defined …

Tamimi RM, Lagiou P, Adami H‐O, Trichopoulos D (Harvard School of Public Health,
Boston, MA, USA; University of Athens Medical School, Goudi, Athens, Greece; and …

The optimal way of dealing with any disease is by prevention. This is particularly true of
cancer, with all of its complexities. A major problem that exists for cancer prevention is that …

Cancer chemoprevention is defined as the use of natural, synthetic, or biologic chemical
agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer. The …

The beneficial and adverse effects of some chemopreventive agents, such as Vitamins A, C,
E, beta-carotene, indole-3-carbinol, capsaicin, garlic, and aloe are reviewed. Two large …