Metastatic disease is the major cause of death in colorectal cancer (CRC) patients. The
metastatic process is highly inefficient and comprises multiple sequential steps. While many …

MicroRNAs (miRNAs) are a type of small non-coding RNA molecule that performs an
important role in post‑transcriptional gene regulation. Since miRNAs were first identified in …

In recent years, there has been a tremendous and growing interest among researchers to
investigate the role of mircoRNA (miRNA) in normal cellular as well as in disease processes …

Colorectal cancer (CRC) is the second leading cause of cancer‐related mortality in Western
countries. Although the aberrant expression of several microRNAs (oncomiRs) is associated …

Cancer is also determined by the alterations of oncogenes and tumor suppressor genes.
These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers …

MicroRNAs (miRNAs) are noncoding RNAs that have been identified as important
posttranscriptional regulators of gene expression. miRNAs production is controlled at …

MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …

Although they account for only a very minor fraction of the expressed genome, microRNAs
(miRNAs) are pivotal regulators of development and cellular homeostasis through their …

Since the discovery of the first microRNA (miRNA), the exploration of miRNA biology has
come to a new era in recent decades. Monumental studies have proven that miRNAs can be …

The knowledge that miRNA expression is frequently dysregulated in cancer has uncovered
an entirely new repertoire of molecular factors upstream of gene expression, with exciting …