Therapy for inflammatory bowel disease (IBD) has changed, with several new agents being
evaluated. The era of anti-tumor necrosis factor (anti-TNF) antibody therapy saw remarkable …

The gastrointestinal tract is lined by a single layer of epithelial cells that secrete mucus
toward the lumen, which collectively separates the immune sentinels in the underlying …

The discovery of cytokines as key drivers of immune-mediated diseases has spurred efforts
to target their associated signalling pathways. Janus kinases (JAKs) are essential signalling …

Purpose of review This article reviews current treatment options and strategies and provides
an update on the status of drug development programs of new therapeutic agents for …

Inflammatory bowel disease (IBD) is a chronic heterogeneous group of diseases that has
undergone major advances in the understanding of its etiology and pathogenesis in recent …