Differential roles of dihydropyridine calcium antagonist nifedipine, nitrendipine and amlodipine on gentamicin-induced renal tubular toxicity in rats

J Li, Q Li, X Xie, Y Ao, C Tie, R Song - European journal of pharmacology, 2009 - Elsevier
In the present study, we investigated the antioxidative potencies of dihydropyridine calcium
antagonists prototype nifedipine, the second generation drug nitrendipine, and the long …

Effects of pre and post-treatments with dipyridamole in gentamicin-induced acute nephrotoxicity in the rat

P Balakumar, WE WitnessKoe, YS Gan… - Regulatory Toxicology …, 2017 - Elsevier
This study investigated the pretreatment and post-treatment effects of dipyridamole (20
mg/kg/day, po) in gentamicin-induced acute nephrotoxicity in rats. Rats were administered …

Agmatine improves renal function in gentamicin-induced nephrotoxicity in rats

DH El-Kashef, AE El-Kenawi, MA Rahim… - Canadian Journal of …, 2016 - cdnsciencepub.com
The present study was designed to explore the possible protective effects of agmatine, a
known nitric oxide (NO) synthase inhibitor, against gentamicin-induced nephrotoxicity in …

[PDF][PDF] Effect of cimetidine on gentamicin-losartan induced-nephrotoxicity in rats

SM Poormoosavi, MA Behmanesh… - Afr J Pharm …, 2010 - academicjournals.org
Drug-induced nephrotoxicity is an important cause of renal failure. Aminoglycoside
antibiotics, such as gentamicin can produce nephrotoxicity, due to in part to an imbalance of …

Cilostazol attenuates gentamicin-induced nephrotoxicity in rats

AA Abdelsameea, AM Mohamed, MG Amer… - … and toxicologic pathology, 2016 - Elsevier
Introduction Gentamycin is a widely used antibiotic. The nephrotoxic adverse effects of the
drug may limit its use. Cilostazol, a phosphodiesterase III inhibitor, was reported to protect …

Salicylic Acid Attenuates Gentamicin‐Induced Nephrotoxicity in Rats

P Randjelovic, S Veljkovic, N Stojiljkovic… - The Scientific World …, 2012 - Wiley Online Library
Gentamicin (GM) is a widely used antibiotic against serious and life‐threatening infections,
but its usefulness is limited by the development of nephrotoxicity. The present study was …

Candesartan and epigallocatechin‐3‐gallate ameliorate gentamicin‐induced renal damage in rats through p38‐MAPK and NF‐κB pathways

HI Ahmed, EA Mohamed - Journal of biochemical and …, 2019 - Wiley Online Library
This study pointed to estimate the possible protective impacts of candesartan and/or
epigallocatechin‐3‐gallate (EGCG) against gentamicin‐induced nephrotoxicity. The current …

The nephroprotective effects of pioglitazone and glibenclamide against gentamicin-induced nephrotoxicity in rats: a comparative study

SI Al-Azzam, KK Abdul-Razzak… - Journal of …, 2010 - Taylor & Francis
The aim of the current study is to comparatively examine the nephroprotective effects of
pioglitazone and glibenclamide in a rat model subjected to gentamicin-induced …

Carvedilol: a beta blocker with antioxidant property protects against gentamicin-induced nephrotoxicity in rats

KV Kumar, AA Shifow, MUR Naidu, KS Ratnakar - Life sciences, 2000 - Elsevier
Gentaraicin is an antibiotic effective against gram negative infections, whose clinical use is
limited by its nephrotoxicity. Since the pathogenesis of gentamicin-induced nephrotoxicity …

[PDF][PDF] Protective effect of taurine and quercetin against renal dysfunction associated with the combined use of gentamycin and diclofenac

AAK Eldin, AA Shaheen, HM Abd Elgawad, NI Shehata - 2008 - scholar.cu.edu.eg
The potential protective effects of taurine and quercetin against gentamycin (GM)/diclofenac
(DC) combined nephrotoxicity were investigated in rats. The results showed that …