In this study, we ask whether antigen presentation can be effected by antigen-activated B
cells. Antigen-dependent in vitro proliferation of T cells from mice primed with SRBC or …

Previous experiments suggested a role for specific B cells in the induction of antigen (SRBC)-
specific T cell proliferation. Two models were proposed: in the first, B cells directly presented …

Abstract Models for T cell: B cell collaboration suggest that activated B cells process and
present Ag to Th cells which subsequently induce B cell proliferation and differentiation. In …

T cells and cytokines were used to activate highly enriched populations of 2, 4, 6-
trinitrophenyl (TNP)-binding B cells (TNP-ABC). TNP-ABC did not proliferate or differentiate …

In vivo experiments were performed to determine if the cross-linking of mlg on antigen-
presenting B cells could induce them to present Ag to naive T cells in a stimulatory rather …

B lymphocytes are regarded as professional antigen-presenting cells (APCs) despite their
primary role in humoral immunity. Over the last two decades, studies designed to define the …

The resting B lymphocyte is all potential, a container for a unique set of antibody genes
created by DNA recombination in the bone marrow. To express its potential as secreted …

The capacity of the trinitrophenyl haptenic group coupled to a series of chemically dissimilar
carriers to cross-stimulate putative T-dependent and T-independent B-cell subpopulations …

The pioneering studies of Miller, Mitchell, Mitchison and others on the role of the thymus in
lymphocyte development led to the realization that there were two classes of lymphocytes, T …

The responsiveness to T-dependent (TD) and T-independent (TI) TNP-antigens of murine
splenic B cells previously enriched for antigen-binding cells (ABC) was examined. TNP-TI …