Predicting treatment response in major depressive disorder: the impact of early symptomatic improvement
Objective: Antidepressants (ADs) are the mainstay of treatment for major depressive
disorder (MDD). Despite their widespread usage, a consensus does not exist as to the …
disorder (MDD). Despite their widespread usage, a consensus does not exist as to the …
Early improvement and response to antidepressant medications in adults with major depressive disorder. Meta-analysis and study of a sample with treatment-resistant …
Background Initial improvement in the first weeks of antidepressant (AD) treatment is a
useful early predictor of complete AD response. We performed a meta-analysis of AD …
useful early predictor of complete AD response. We performed a meta-analysis of AD …
Early improvement as a resilience signal predicting later remission to antidepressant treatment in patients with major depressive disorder: systematic review and meta …
S Wagner, A Engel, J Engelmann, D Herzog… - Journal of psychiatric …, 2017 - Elsevier
Early improvement of depressive symptoms during the first two weeks of antidepressant
treatment has been discussed to be a resilience signal predicting a later positive treatment …
treatment has been discussed to be a resilience signal predicting a later positive treatment …
Predicting antidepressant response by monitoring early improvement of individual symptoms of depression: individual patient data meta-analysis
YA de Vries, AM Roest, EH Bos… - The British Journal of …, 2019 - cambridge.org
BackgroundImprovement in depression within the first 2 weeks of antidepressant treatment
predicts good outcomes, but non-improvers can still respond or remit, whereas improvers …
predicts good outcomes, but non-improvers can still respond or remit, whereas improvers …
Does early improvement triggered by antidepressants predict response/remission?—Analysis of data from a naturalistic study on a large sample of inpatients with …
V Henkel, F Seemüller, M Obermeier, M Adli… - Journal of affective …, 2009 - Elsevier
BACKGROUND: Delayed onset of efficacy of antidepressants and a high proportion of
depressed patients being poor or non-responders to antidepressants are well known clinical …
depressed patients being poor or non-responders to antidepressants are well known clinical …
[HTML][HTML] Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial
BW Dunlop, EB Binder, JF Cubells, MM Goodman… - Trials, 2012 - Springer
Background Limited controlled data exist to guide treatment choices for clinicians caring for
patients with major depressive disorder (MDD). Although many putative predictors of …
patients with major depressive disorder (MDD). Although many putative predictors of …
The early improvement of depressive symptoms as a potential predictor of response to antidepressants in depressive patients who failed to respond to previous …
M Bares, T Novak, M Kopecek, P Stopkova, J Kozeny… - European …, 2012 - Elsevier
INTRODUCTION: Current studies suggest that improvement of depressive symptoms after 2
weeks of treatment could predict the subsequent response. The aim of our study was to …
weeks of treatment could predict the subsequent response. The aim of our study was to …
Predictability of nonremitting depression after first 2 weeks of antidepressant treatment: a VAST-D trial report
PB Hicks, V Sevilimedu, GR Johnson… - … and clinical practice, 2019 - Am Psychiatric Assoc
Objective: In this secondary analysis of data from the Veterans Affairs Augmentation and
Switching Treatments for Improving Depression Outcomes (VAST-D) study, the authors …
Switching Treatments for Improving Depression Outcomes (VAST-D) study, the authors …
Using patient self-reports to study heterogeneity of treatment effects in major depressive disorder
Backgrounds. Clinicians need guidance to address the heterogeneity of treatment
responses of patients with major depressive disorder (MDD). While prediction schemes …
responses of patients with major depressive disorder (MDD). While prediction schemes …
Early improvement in the first 2 weeks as a predictor of treatment outcome in patients with major depressive disorder: a meta-analysis including 6562 patients.
A Szegedi, WT Jansen… - Journal of Clinical …, 2009 - psychiatrist.com
Objective: New evidence indicates that treatment response can be predicted with high
sensitivity after 2 weeks of treatment. Here, we assess whether early improvement with …
sensitivity after 2 weeks of treatment. Here, we assess whether early improvement with …