The American Society of Regional Anesthesia and Pain Medicine Practice Advisory on
Local Anesthetic Systemic Toxicity assimilates and summarizes current knowledge …

Abstract In 2010, the American Society of Regional Anesthesia and Pain Medicine (ASRA)
issued a practice advisory on local anesthetic systemic toxicity (LAST). The executive …

Abstract The American Society of Regional Anesthesia and Pain Medicine (ASRA)
periodically revises and updates its checklist for the management of local anesthetic …

Local anesthetic systemic toxicity (LAST) is a life-threatening adverse event that may occur
after the administration of local anesthetic drugs through a variety of routes. Increasing use …

Although new drugs and techniques may improve outcomes when unintended high blood
levels of local anesthetics occur, the primary focus of daily practice should remain the …

Purpose Regional anesthesia is enjoying a renaissance due in part to the advent of
ultrasound guidance and the development of new techniques such as tissue plane blocks …

Despite advances in clinical practice, local anaesthetic systemic toxicity continues to occur
with the therapeutic use of local anaesthesia. Patterns of presentation have evolved over …

Severe, systemic local anesthetic toxicity is arguably the most feared complication of
regional anesthesia. A combination of old and new therapies is recommended to reduce the …

Abstract The American Society of Regional Anesthesia and Pain Medicine's Third Practice
Advisory on local anesthetic systemic toxicity is an interim update from its 2010 advisory …

The classic description of local anesthetic systemic toxicity (LAST) generally described in
textbooks includes a series of progressively worsening neurologic symptoms and signs …