Neuropsychiatric disturbances (NPDs) are considered hallmarks of Alzheimer's disease
(AD). Nevertheless, treatment of these symptoms has proven difficult and development of …

Early Alzheimer's disease (AD) and depression share many symptoms, thus it is very difficult
to initially distinguish one from the other. Therefore, characterizing the shared and different …

Alzheimer's disease (AD) is a progressive, dementing, whole-body disorder that presents
with decline in cognitive, behavioral, and emotional functions, as well as endocrine …

Emerging evidence suggests that sleep deprivation (SD) is a public health epidemic and
increase the risk of Alzheimer's disease (AD) progression. However, the underlying …

Early Alzheimer's disease (AD) and depression share many symptoms, but the underlying
mechanisms are not clear. Therefore, characterizing the shared and different biological …

Alzheimer's disease (AD) is often accompanied by changes in mood as well as increases in
circulating cortisol levels, suggesting that regulation of the stress responsive hypothalamic …

Degeneration of locus ceruleus neurons and subsequent reduction of norepinephrine
concentration in locus ceruleus projection areas represent an early pathological indicator of …

Depression is among the most frequent psychiatric comorbid conditions in Alzheimer
disease (AD). However, pharmacotherapy for depressive disorders in AD is still a big …

Exposure to chronic stress or elevated glucocorticoid hormone levels in adult life has been
associated with cognitive deficits and an increased risk for Alzheimer's disease (AD). Since …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive deficits. Sleep deprivation (SD) could lead to memory deficits, and it was a …