Cell membrane as a promising therapeutic target: from materials design to biomedical applications

X Wu, JJ Hu, J Yoon - Angewandte Chemie, 2024 - Wiley Online Library
The cell membrane is a crucial component of cells, protecting their integrity and stability
while facilitating signal transduction and information exchange. Therefore, disrupting its …

Multifunctional cell membranes-based nano-carriers for targeted therapies: a review of recent trends and future perspective

M Li, Q Guo, C Zhong, Z Zhang - Drug delivery, 2023 - Taylor & Francis
Nanotechnology has ignited a transformative revolution in disease detection, prevention,
management, and treatment. Central to this paradigm shift is the innovative realm of cell …

Biomembrane-based nanostructures for cancer targeting and therapy: from synthetic liposomes to natural biomembranes and membrane-vesicles

J Wang, M Zhu, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
The translational success of liposomes in chemotherapeutics has already demonstrated the
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …

Cell membrane nanotherapeutics: from synthesis to applications emerging tools for personalized cancer therapy

C Sevencan, RSA McCoy, P Ravisankar… - Advanced …, 2020 - Wiley Online Library
Over the last decade, researchers have focused on developing an ideal cancer
nanomedicine with robust biointerfacing, precise tumor targeting, and effective tumor killing …

In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Recent advances in biological membrane-based nanomaterials for cancer therapy

M Shen, X Wu, M Zhu, X Yi - Biomaterials Science, 2022 - pubs.rsc.org
Nanomaterials have shown significant advantages in cancer theranostics, owing to their
enhanced permeability and retention effect in tumors and multi-function integration …

Exogenous agents that target transmembrane domains of proteins

H Yin - Angewandte Chemie International Edition, 2008 - Wiley Online Library
Although membrane proteins account for approximately one third of all proteins encoded in
the human genome, the functions and structures of their transmembrane domains are much …

Recent advances of membrane-cloaked nanoplatforms for biomedical applications

X Ai, M Hu, Z Wang, W Zhang, J Li, H Yang… - Bioconjugate …, 2018 - ACS Publications
In terms of the extremely small size and large specific surface area, nanomaterials often
exhibit unusual physical and chemical properties, which have recently attracted …

[HTML][HTML] Engineered cell membrane-derived nanocarriers: the enhanced delivery system for therapeutic applications

B Yu, X Xue, Z Yin, L Cao, M Li… - Frontiers in cell and …, 2022 - frontiersin.org
There has been a rapid development of biomimetic platforms using cell membranes as
nanocarriers to camouflage nanoparticles for enhancing bio-interfacial capabilities. Various …

Drugging membrane protein interactions

H Yin, AD Flynn - Annual review of biomedical engineering, 2016 - annualreviews.org
The majority of therapeutics target membrane proteins, accessible on the surface of cells, to
alter cellular signaling. Cells use membrane proteins to transduce signals into cells …