Adenosine A2A-D2 receptor-receptor interactions in putative heteromers in the regulation of the striato-pallidal gaba pathway: possible relevance for parkinson's …
S Beggiato, T Antonelli, MC Tomasini… - Current Protein and …, 2014 - ingentaconnect.com
Striatal dopamine adenosine A2A and D2 receptors interact to modulate some aspects of
motor and motivational function. The demonstration of A2A/D2 receptor heteromerization in …
motor and motivational function. The demonstration of A2A/D2 receptor heteromerization in …
[HTML][HTML] Decreased striatal adenosine A2A-dopamine D2 receptor heteromerization in schizophrenia
M Valle-León, LF Callado, E Aso… - …, 2021 - nature.com
According to the adenosine hypothesis of schizophrenia, the classically associated
hyperdopaminergic state may be secondary to a loss of function of the adenosinergic …
hyperdopaminergic state may be secondary to a loss of function of the adenosinergic …
[HTML][HTML] Adenosine A2A Receptors in Striatal Glutamatergic Terminals and GABAergic Neurons Oppositely Modulate Psychostimulant Action and DARPP-32 …
HY Shen, PM Canas, P Garcia-Sanz, JQ Lan… - PLoS …, 2013 - journals.plos.org
Adenosine A2A receptors (A2AR) are located postsynaptically in striatopallidal GABAergic
neurons, antagonizing dopamine D2 receptor functions, and are also located …
neurons, antagonizing dopamine D2 receptor functions, and are also located …
Adenosine A2A receptors in neuroadaptation to repeated dopaminergic stimulation: Implications for the treatment of dyskinesias in Parkinson's disease
JF Chen, S Fredduzzi, E Bastia, L Yu, R Moratalla… - Neurology, 2003 - AAN Enterprises
The A2A receptor has recently attracted considerable interest as a potential target for
Parkinson's disease (PD) therapy based on the motor-enhancing and neuroprotective …
Parkinson's disease (PD) therapy based on the motor-enhancing and neuroprotective …
An update on adenosine A2A receptors as drug target in Parkinson's disease
A Vallano, V Fernandez-Duenas… - CNS & Neurological …, 2011 - ingentaconnect.com
Adenosine receptors are G protein-coupled receptors (GPCRs) that mediate the
physiological functions of adenosine. In the central nervous system adenosine A2A …
physiological functions of adenosine. In the central nervous system adenosine A2A …
Adenosine–dopamine interactions in the pathophysiology and treatment of CNS disorders
K Fuxe, D Marcellino… - CNS neuroscience & …, 2010 - Wiley Online Library
Adenosine–dopamine interactions in the central nervous system (CNS) have been studied
for many years in view of their relevance for disorders of the CNS and their treatments. The …
for many years in view of their relevance for disorders of the CNS and their treatments. The …
Impact of an Adenosine A2A Receptor Agonist and Antagonist on Binding of the Dopamine D2 Receptor Ligand [11C]raclopride in the Rodent Striatum
K Prasad, EFJ de Vries, JWA Sijbesma… - Molecular …, 2022 - ACS Publications
Adenosine A2A and dopamine D2 receptors in the basal ganglia form heterotetrameric
structures that are involved in the regulation of motor activity and neuropsychiatric functions …
structures that are involved in the regulation of motor activity and neuropsychiatric functions …
Adenosine A2A receptors, dopamine D2 receptors and their interactions in Parkinson's disease
K Fuxe, D Marcellino, S Genedani… - … : official journal of the …, 2007 - Wiley Online Library
Future therapies in Parkinson's disease may substantially build on the existence of intra‐
membrane receptor–receptor interactions in DA receptor containing heteromeric receptor …
membrane receptor–receptor interactions in DA receptor containing heteromeric receptor …
[HTML][HTML] Adenosine A2A-dopamine D2 receptor heteromers operate striatal function: impact on parkinson's disease pharmacotherapeutics
V Fernandez-Duenas, S Ferré… - Neural Regeneration …, 2018 - journals.lww.com
The basal ganglia (BG) assemble a series of deep gray matter structures forming recurrent
loops that include the cortex and thalamus, and that participate in the regulation of a …
loops that include the cortex and thalamus, and that participate in the regulation of a …
[HTML][HTML] Pharmacological interactions between adenosine A2A receptor antagonists and different neurotransmitter systems
A Pinna, M Serra, J Marongiu, M Morelli - Parkinsonism & Related …, 2020 - Elsevier
While Parkinson's disease (PD) is traditionally characterized by dopaminergic neuron
degeneration, several neurotransmitters and neuromodulators besides dopamine are also …
degeneration, several neurotransmitters and neuromodulators besides dopamine are also …