Overview of serum uric acid treatment targets in gout: why less than 6 mg/dL?

G Ruoff, NL Edwards - Postgraduate medicine, 2016 - Taylor & Francis
Gout is a progressive, painful, debilitating form of inflammatory arthritis. It is caused by
factors that elevate the concentration of serum uric acid (sUA), leading to hyperuricemia …

Critical appraisal of serum urate targets in the management of gout

LK Stamp, N Dalbeth - Nature Reviews Rheumatology, 2022 - nature.com
Gout management involves two broad aspects: treatment of gout flares to provide rapid
symptomatic relief and long-term urate-lowering therapy to lower serum urate sufficiently to …

Management of gout and hyperuricemia: multidisciplinary consensus in Taiwan

KH Yu, DY Chen, JH Chen, SY Chen… - … journal of rheumatic …, 2018 - Wiley Online Library
Gout is an inflammatory disease manifested by the deposition of monosodium urate (MSU)
crystals in joints, cartilage, synovial bursa, tendons or soft tissues. Gout is not a new disease …

Hyperuricemia and gout: new concepts in diagnosis and management

PP Doghramji, RL Wortmann - Postgraduate medicine, 2012 - Taylor & Francis
Gout is a chronic, progressive condition for which hyperuricemia is the primary risk factor.
The initial episodes of gout may be brief, only lasting for 3 to 5 days, and patients may …

Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors

M Dehlin, L Jacobsson, E Roddy - Nature Reviews Rheumatology, 2020 - nature.com
Gout is the most common inflammatory arthritis and occurs when hyperuricaemia, sustained
elevation of serum urate levels resulting in supersaturation of body tissues with urate, leads …

Optimizing current treatment of gout

F Rees, M Hui, M Doherty - Nature Reviews Rheumatology, 2014 - nature.com
Gout is the most common inflammatory arthritis worldwide. Although effective treatments
exist to eliminate sodium urate crystals and to'cure'the disease, the management of gout is …

Therapeutic approaches to chronic hyperuricemia and gout

D Grassi, R Pontremoli, R Bocale, C Ferri… - High Blood Pressure & …, 2014 - Springer
Gout is currently one of the most common causes of inflammatory arthritis in most
industrialised countries. Apart from its high frequency, gout is associated with disability, poor …

Gout: an update

AT Eggebeen - American family physician, 2007 - aafp.org
Arthritis caused by gout (ie, gouty arthritis) accounts for millions of outpatient visits annually,
and the prevalence is increasing. Gout is caused by monosodium urate crystal deposition in …

Long-term management of gout: nonpharmacologic and pharmacologic therapies

Y Chaichian, S Chohan… - Rheumatic Disease …, 2014 - rheumatic.theclinics.com
The clinical signs and symptoms of gout reflect inflammatory responses to monosodium
urate crystals deposited in tissues from extracellular fluids saturated for urate. 1 …

Difficult-to-treat gouty arthritis: a disease warranting better management

N Schlesinger - Drugs, 2011 - Springer
Gouty arthritis is the most common inflammatory arthritis in adults and is characterized by
very painful flares. Gouty arthritis results from an elevated body uric acid pool, which leads to …