Is n-pentane really an index of lipid peroxidation in humans and animals? A methodological reevaluation

D Kohlmuller, W Kochen - Analytical biochemistry, 1993 - Elsevier
Volatile hydrocarbons such as ethane and n-pentane are known to originate from
peroxidation of polyunsaturated fatty acids in membrane lipids and they are accepted as a …

Concentrating breath samples using liquid nitrogen: a reliable method for the simultaneous determination of ethane and pentane

MD Knutson, FE Viteri - Analytical biochemistry, 1996 - Elsevier
The measurement of ethane and pentane in breath offers a sensitive and noninvasive
means to assessin vivolipid peroxidation in animals and humans. However, numerous …

Methods for measuring ethane and pentane in expired air from rats and humans

MD Knutson, GJ Handelman, FE Viteri - Free Radical Biology and …, 2000 - Elsevier
Numerous studies in animals and humans provide evidence that ethane and pentane in
expired air are useful markers of in vivo lipid peroxidation. The measurement of breath …

Monitoring lipid peroxidation by breath analysis: endogenous hydrocarbons and their metabolic elimination

H Frank, T Hintze, D Bimboes, H Remmer - Toxicology and Applied …, 1980 - Elsevier
Monitoring of ethane and pentane in breath as a noninvasive method to measure lipid
peroxidation is performed by an increasing number of laboratories. The alkanes are …

Pitfalls in the use of breath pentane measurements to assess lipid peroxidation.

JR Springfield, MD Levitt - Journal of lipid research, 1994 - ASBMB
Literature values for breath pentane, an indicator of lipid peroxidation, vary by 1,000-fold in
healthy subjects. This report describes multiple technical artifacts that may explain this …

Pentane measurement in man as an index of lipoperoxidation

J Pincemail, C Deby, A Dethier, Y Bertrand… - Bioelectrochemistry and …, 1987 - Elsevier
The peroxidation of unsaturated fatty acids, constituents of tissues, is one proposed
mechanism of invivo oxidant damage. Several methods are described to quantify in vivo …

Breath alkanes as an index of lipid peroxidation

A Van Gossum, J Decuyper - European Respiratory Journal, 1989 - Eur Respiratory Soc
Formation of free radicals and lipid peroxidation are mechanisms that are involved in many
conditions including cellular damage. In a human body, there are many antioxidant systems …

Quantitative evaluation of ethane and n-pentane as indicators of lipid peroxidation in vivo

JG Filser, HM Bolt, H Muliawan, H Kappus - Archives of Toxicology, 1983 - Springer
The use of exhalation of ethane and n-pentane in experimental animals as parameters of
lipid peroxidation led to an examination of pharmacokinetics of both compounds in rats …

The potential of the hydrocarbon breath test as a measure of lipid peroxidation

CMF Kneepkens, G Lepage, CC Roy - Free Radical Biology and Medicine, 1994 - Elsevier
The straight chain aliphatic hydrocarbons ethane and pentane have been advocated as
noninvasive markers of free-radical induced lipid peroxidation in humans. In in vitro studies …

Is pentane a normal constituent of human breath?

A Cailleux, P Allain - Free radical research communications, 1993 - Taylor & Francis
Breath analysis is a non-invasive method for investigation of the volatile compounds
produced by humans. Pentane has often been taken as an indicator of lipid peroxidation …