Helminth infections, which are prevalent in areas where malaria is endemic, have been
shown to modulate immune responses to unrelated pathogens and have been implicated in …

Helminthiases, which are highly prevalent in areas where malaria is endemic, have been
shown to modulate or suppress the immune response to unrelated antigens or pathogens. In …

Malaria is still responsible for up to 1 million deaths per year worldwide, highlighting the
need for protective malaria vaccines. Helminth infections that are prevalent in malaria …

Chronic helminth infections induce strong type 2 and regulatory immune responses and are
known to influence immune activity to other antigens such as allergens and vaccines. Since …

Development of an effective vaccine against malaria remains a priority. However, a
significant number of individuals living in tropical areas are also likely to be co-infected with …

We investigated malaria-associated pathology in mice co-infected with Heligmosomoides
polygyrus (Hp) and Plasmodium chabaudi AS (Pc). Despite higher peak parasitemia, co …

Mixed parasite infections are common in many parts of the world, but little is known of the
effects of concomitant parasite infections on the immune response or severity of clinical …

The promising malaria vaccine candidates that have been tested in the field have, so far,
yielded disappointing and, at times, conflicting results. Considerable efforts are being made …

Vaccine development for the blood stages of malaria has focused on the induction of
antibodies to parasite surface antigens, most of which are highly polymorphic. An alternate …

Background Helminths can modulate the host immune response to Plasmodium falciparum
and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth …