Peroxisomes are single membrane-bound organelles present in virtually all eukaryotes.
These organelles participate in several important metabolic processes, and defects in …

In peroxisome formation, models of near‐autonomous peroxisome biogenesis with
membrane protein integration directly from the cytosol into the peroxisomal membrane are in …

The endoplasmic reticulum (ER) plays an important role in peroxisome biogenesis; some
peroxisomal membrane proteins are inserted into the ER and trafficked to peroxisomes in …

Sec16 plays a key role in the formation of coat protein II vesicles, which mediate protein
transport from the endoplasmic reticulum (ER) to the Golgi apparatus. Mammals have two …

Two pathways have been identified for peroxisome formation:(i) growth and division and (ii)
de novo synthesis. Recent experiments determined that peroxisomes originate at the …

The origin of peroxisomes has long been disputed. However, recent evidence suggests that
peroxisomes can be formed de novo from the endoplasmic reticulum (ER) in yeast and …

Dynamic control of peroxisome proliferation is integral to the peroxisome's many functions.
The endoplasmic reticulum (ER) serves as a source of preperoxisomal vesicles (PPVs) that …

Peroxisomes, as well as the signals and the machinery that target proteins to this organelle,
are conserved in most eukaryotic organisms. Different peroxisomal targeting signals (PTSs) …

Proteins are targeted to the membrane and matrix of peroxisomes by distinct pathways.
Recent observations suggest a further route: a subset of peroxisomal membrane proteins …

Pex19p, a soluble cytoplasmic transport protein, is required for the traffic of the peroxisomal
membrane proteins Pex3p and Pex15p from the endoplasmic reticulum (ER) to the …