Key to the coordination of the functions of individ-ual cells within the intact organism is
intercellular communication, a means by which the individual cell is regulated in its …

Intercellular and intracellular communication is of critical importance to the organization,
differentiation, and coordination of all complex living systems. The need to maintain …

The concept of recognition of extracellular messengers by membrane-bound or internal
molecules which translate ligand binding into cell activation has, in the last decade, led to …

The cloning, sequencing, and expression of a variety of membrane receptors and channels
indicate the existence of at least four" superfamilies" of molecular structures that mediate …

More than 60% of the current drugs are based on G protein-coupled receptors.
Paradoxically, high-resolution structures are not available to facilitate rational drug design …

G protein–coupled receptors are present on every excitable and regulatable cell in the body
and represent important potential sites for drug action. This group of molecules already …

Covering recently developed methods in membrane-bound receptors, this book emphasizes
receptor structure and function, knowledge of which is essential to the study of signal …

Life implies organization and thus regulation. This requires intraand intercellular
communication and communication with the environment. The exchange of information is to …

G protein-coupled receptors (GPCRs) constitute the largest family of cell-surface receptors,
with more than 800 members identified thus far in the human genome. They regulate the …

Cell surface receptors play a central role in the regulation of both cellular and systemic
physiology by mediating intercellular communication, facilitating protein trafficking, and …