LncRNA MALAT1-related signaling pathways in osteosarcoma

M Farzaneh, S Najafi, O Anbiyaee, S Azizidoost… - Clinical and …, 2023 - Springer
Osteosarcoma (OS) is a common and malignant form of bone cancer, which affects children
and young adults. OS is identified by osteogenic differentiation and metastasis. However …

[HTML][HTML] Long noncoding RNA MALAT1 promotes cell proliferation through suppressing miR-205 and promoting SMAD4 expression in osteosarcoma

Q Li, X Pan, X Wang, X Jiao, J Zheng, Z Li, Y Huo - Oncotarget, 2017 - ncbi.nlm.nih.gov
Increasing evidences have indicated that long non-coding RNAs (lncRNAs) play an
important role in multiply biological processes including cell development, differentiation …

[HTML][HTML] LncRNA MALAT1 promotes cancer metastasis in osteosarcoma via activation of the PI3K-Akt signaling pathway

Y Chen, W Huang, W Sun, B Zheng, C Wang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: LncRNAs have been reported to be vital regulators of the progression of
osteosarcoma, although the underlying mechanisms are not completely understood …

MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway

Y Dong, G Liang, BO Yuan, C Yang, R Gao, X Zhou - Tumor Biology, 2015 - Springer
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), one of the first found
cancer-associated long noncoding RNAs (lncRNAs), involves in the development and …

[HTML][HTML] MALAT1 promotes osteosarcoma development by targeting TGFA via MIR376A

W Luo, H He, W Xiao, Q Liu, Z Deng, Y Lu, Q Wang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long non-coding
RNA (lncRNA) that contributes to the initiation and development of many solid tumors …

Long noncoding RNA MALAT1 as a potential therapeutic target in osteosarcoma

X Cai, Y Liu, W Yang, Y Xia, C Yang… - Journal of …, 2016 - Wiley Online Library
Recent studies have revealed that long noncoding RNA metastasis‐associated lung
adenocarcinoma transcript 1 (MALAT1) plays an important role in the development of …

[HTML][HTML] LncRNA MALAT1 facilitates lung metastasis of osteosarcomas through miR-202 sponging

J Zhang, CD Piao, J Ding, ZW Li - Scientific Reports, 2020 - nature.com
Lungs are the primary metastatic sites for osteosarcomas responsible for associated
mortality. Recent data has documented role of long non-coding RNAs (lncRNAs) in …

[HTML][HTML] MALAT1 predicts poor survival in osteosarcoma patients and promotes cell metastasis through associating with EZH2

Y Huo, Q Li, X Wang, X Jiao, J Zheng, Z Li, X Pan - Oncotarget, 2017 - ncbi.nlm.nih.gov
Osteosarcoma is the most common type of bone cancer, especially in children and young
adults. Recently, long noncoding RNAs (lncRNAs) have emerged as new prognostic …

[HTML][HTML] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

G Duan, C Zhang, C Xu, C Xu… - International …, 2019 - spandidos-publications.com
Long non‑coding (lnc) RNAs have been demonstrated to be involved in the development of
various types of cancers, such as osteosarcoma (OS). Long non‑coding (lnc) RNA …

MALAT1 Promotes the Proliferation and Metastasis of Osteosarcoma Cells By Activating the Rac1/JNK Pathway Via Targeting MiR-509.

Y Zhang, Q Dai, F Zeng, H Liu - Oncology Research, 2018 - europepmc.org
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long noncoding
RNA (lncRNA) that contributes to the initiation and development of many solid tumors …