Interleukin 10 promoter region polymorphisms in inflammatory bowel disease in Tunisian population

R Marrakchi, A Moussa, S Ouerhani, K Bougatef… - Inflammation …, 2009 - Springer
Objective: To test whether IL-10 promoter region polymorphisms are associated with
susceptibility to inflammatory bowel disease, we examined the contribution of interleukin-10 …

The polymorphism rs3024505 (C/T) downstream of the IL10 gene is associated with Crohn's disease in Serbian patients with inflammatory bowel disease

D Mijac, IV Petrovic, S Djuranovic, V Perovic… - The Tohoku Journal of …, 2016 - jstage.jst.go.jp
Inflammatory bowel disease (IBD), manifesting as Crohn's disease (CD) and ulcerative
colitis (UC), is characterized by recurring episodes of inflammation in gastrointestinal tract, in …

Interleukin-4 and interleukin-10 gene polymorphisms in patients with inflammatory bowel disease

N Ebrahimi Daryani, A Saghazadeh… - Immunological …, 2017 - Taylor & Francis
Background: Changes in cytokine expression have been frequently found in patients with
inflammatory bowel disease (IBD). Cytokine values outside the normal range may be …

Interleukin-10 promoter polymorphisms influence susceptibility to ulcerative colitis in a gender-specific manner

A Tedde, A Laura Putignano, S Bagnoli… - Scandinavian journal …, 2008 - Taylor & Francis
Objective. Pathological evidence supports a potential role of the pro-and anti-inflammatory
cytokine network in the pathogenesis of inflammatory bowel disease (IBD). Moreover …

Interleukin-10 polymorphisms in Spanish patients with IBD

L Fernandez, A Martinez, JL Mendoza… - Inflammatory bowel …, 2005 - academic.oup.com
Background Inflammatory bowel disease (IBD) is considered a heterogeneous, complex
polygenic disease where both genetic and environmental factors are involved in the …

Role of polymorphisms in the interleukin-10 gene in determining disease susceptibility and phenotype in inflamatory bowel disease

GP Aithal, A Craggs, CP Day, M Welfare… - Digestive diseases and …, 2001 - Springer
Abstract Interleukin-10 (IL-10) has a key role in regulating mucosal inflammation. The role of
functional polymorphisms at positions− 627 and− 1117 in the IL-10 gene as candidate …

The association between three promoter polymorphisms of IL-10 and inflammatory bowel diseases (IBD): a meta-analysis

L Zou, L Wang, X Gong, H Zhao, A Jiang, S Zheng - Autoimmunity, 2014 - Taylor & Francis
Aim: To assess the relationship of the Interleukin-10 (IL-10)-1082G/A (rs1800896),-819C/T
(rs1800871) and-592C/A (rs1800872) polymorphism with inflammatory bowel disease (IBD) …

Association between polymorphisms in the promoter region of interleukin-10 and susceptibility to inflammatory bowel disease

H Lv, Y Jiang, J Li, M Zhang, Z Shang, J Zheng… - Molecular biology …, 2014 - Springer
The aim of this study was to assess the association of polymorphisms in the promoter region
of the IL-10 gene with the risk of inflammatory bowel disease (IBD), including Crohn's …

[PDF][PDF] Polymorphisms in the interleukin-10 gene and relation to phenotype in patients with ulcerative colitis

JL Mendoza, E Urcelay, R Lana, A Martínez… - Revista espanola de …, 2006 - academia.edu
ABSTRACT Background and objectives: interleukin-10 (IL-10) has a key role in regulating
mucosal inflammation in inflammatory bowel disease. In our population of Spanish …

Interleukin‐10 (IL‐10) genotypes in inflammatory bowel disease

A Tagore, WM Gonsalkorale, V Pravica… - Tissue …, 1999 - Wiley Online Library
Interleukin‐10 (IL‐10) is an anti‐inflammatory cytokine. Its production in humans is under
genetic control, and genotype defines high or low producers of this cytokine. This study …