Stem cell division is essential for tissue integrity during growth, aging, and pathogenic
assaults. Adult gastrointestinal tract encounters numerous stimulations, and impaired tissue …

Stem cell‐mediated tissue repair is a promising approach for many diseases. Mammalian
intestine is an actively regenerating tissue such that epithelial cells are constantly shedding …

Drosophila has long been an excellent model organism for studying stem cell biology.
Notably, studies of Drosophila's germline stem cells have been instrumental in developing …

Adult tissue homeostasis requires a tight balance between the removal of old or damaged
cells and the production of new ones. Such processes are usually driven by dedicated stem …

Stem cells have essential functions in the development and maintenance of our organs.
Improper regulation of adult stem cells and tissue homeostasis can result in cancers and …

Epithelial cells of the digestive tracts of most animals are short-lived, and are constantly
replenished by the progeny of long-lived, resident intestinal stem cells. Proper regulation of …

Many adult tissues and organs are maintained by resident stem cells that are activated in
response to injury but the mechanisms that regulate stem cell activity during regeneration …

Many adult tissues and organs including the intestine rely on resident stem cells to maintain
homeostasis and regeneration. In mammals, the progenies of intestinal stem cells (ISCs) …

Drosophila adult midgut intestinal stem cells (ISCs) maintain tissue homeostasis by
producing progeny that replace dying enterocytes and enteroendocrine cells. ISCs adjust …

Maintenance of tissue homeostasis is critical in tissues with high turnover such as the
intestinal epithelium. The intestinal epithelium is under constant cellular assault due to its …