Near infrared photoimmunotherapy with combined exposure of external and interstitial light sources

Y Maruoka, T Nagaya, K Sato, F Ogata… - Molecular …, 2018 - ACS Publications
Near infrared photoimmunotherapy (NIR-PIT) is a new target-cell-specific cancer treatment
that induces highly selective necrotic/immunogenic cell death after systemic administration …

Evaluation of early therapeutic effects after near-infrared photoimmunotherapy (NIR-PIT) using luciferase–luciferin photon-counting and fluorescence imaging

Y Maruoka, T Nagaya, Y Nakamura, K Sato… - Molecular …, 2017 - ACS Publications
Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed cancer treatment that
induces highly selective immunogenic cell death. It is based on an antibody–photoabsorber …

[HTML][HTML] Interstitial near-infrared photoimmunotherapy: effective treatment areas and light doses needed for use with fiber optic diffusers

S Okuyama, T Nagaya, K Sato, F Ogata, Y Maruoka… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Near-infrared photoimmunotherapy (NIR-PIT), a promising cancer therapy utilizing an
antibody-photoabsorber conjugate (APC) and NIR light, which induces rapid necrotic cell …

Near infrared photoimmunotherapy; a review of targets for cancer therapy

T Kato, H Wakiyama, A Furusawa, PL Choyke… - Cancers, 2021 - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed cancer
treatment that uses an antibody-photoabsorber (IRDye700DX) conjugate (APC) that is …

[HTML][HTML] Near-infrared photoimmunotherapy: a comparison of light dosing schedules

F Ogata, T Nagaya, Y Nakamura, K Sato, S Okuyama… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Near infrared photoimmunotherapy (NIR-PIT) is a newly-developed cancer therapy in which
a monoclonal antibody is conjugated to a near-infrared photoabsorber, IR700 to form an …

Selection of antibody and light exposure regimens alters therapeutic effects of EGFR-targeted near-infrared photoimmunotherapy

R Okada, T Kato, A Furusawa, F Inagaki… - Cancer Immunology …, 2022 - Springer
Near-infrared photoimmunotherapy (NIR-PIT) is a cell-specific cancer therapy that uses an
antibody-photoabsorber (IRDye700DX, IR700) conjugate (APC) and NIR light. Intravenously …

Near infrared photoimmunotherapy in a transgenic mouse model of spontaneous epidermal growth factor receptor (EGFR)-expressing lung cancer

Y Nakamura, ZW Ohler, D Householder… - Molecular cancer …, 2017 - AACR
Near infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that combines the
specificity of antibodies for targeting tumors with the toxicity induced by a sensitive …

Immediate in vivo target-specific cancer cell death after near infrared photoimmunotherapy

M Mitsunaga, T Nakajima, K Sano, G Kramer-Marek… - BMC cancer, 2012 - Springer
Background Near infrared (NIR) photoimmunotherapy (PIT) is a new type of cancer
treatment based on a monoclonal antibody (mAb)-NIR phthalocyanine dye,(IR700) …

Hurdles for the wide implementation of photoimmunotherapy

K Matsuoka, M Sato, K Sato - Immunotherapy, 2021 - Taylor & Francis
Near infrared photoimmunotherapy (NIR-PIT) is a molecularly targeted treatment for cancers
achieved by injecting a conjugate of IRDye700DX®(IR700), a water-soluble silicon …

[HTML][HTML] Near infrared photoimmunotherapy prevents lung cancer metastases in a murine model

K Sato, T Nagaya, Y Nakamura, T Harada, PL Choyke… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Near infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that combines the
specificity of intravenously injected antibodies with the acute toxicity induced by …