The Glymphatic System (GS) has been proposed as a mechanism to clear brain tissue from
waste. Its dysfunction might lead to several brain pathologies, including the Alzheimer's …

The glymphatic system is a low resistance pathway, by which cerebrospinal fluid enters the
brain parenchyma along perivascular spaces via AQP4 channels. It is hypothesised that the …

The present study aimed to confirm the hypothesis that aquaporin-4 water channels (AQP4)
control solute transition into the brain parenchyma using image analysis of gadolinium …

The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the
brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately …

The glymphatic system transports cerebrospinal fluid (CSF) into the brain via arterial
perivascular spaces and removes interstitial fluid from the brain along perivenous spaces …

The blood–brain barrier (BBB), which imposes significant water permeability restriction,
effectively isolates the brain from the systemic circulation. Seemingly paradoxical, the …

The recently proposed glymphatic pathway for solute transport and waste clearance from the
brain has been the focus of intense debate. By exploiting an isotopically enriched MRI …

Neuroimaging with diffusion-weighted imaging is routinely used for clinical
diagnosis/prognosis. Its quantitative parameter, the apparent diffusion coefficient (ADC), is …

The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the
accumulation of amyloid-β. Influx of cerebrospinal fluid (CSF) depends upon the expression …

There is currently a lack of non-invasive tools to assess water transport in healthy and
pathological brain tissue. Aquaporin-4 (AQP4) water channels are central to many water …