This review presents an overview of the dynamically developing field of mass spectrometry‐
based metabolomics. Metabolomics aims at the comprehensive and quantitative analysis of …

Preprocessing data in a reproducible and robust way is one of the current challenges in
untargeted metabolomics workflows. Data curation in liquid chromatography–mass …

Recent advances in metabolomics-based approaches using liquid or gas chromatography
coupled to high-resolution mass spectrometry (HRMS) offer exciting perspectives to detect …

A current and significant limitation to metabolomics is the large-scale, high-throughput
conversion of raw chromatographically coupled mass spectrometry datasets into organized …

Metabolites are building blocks of cellular function. These species are involved in enzyme-
catalyzed chemical reactions and are essential for cellular function. Upstream biological …

High-resolution mass spectrometry (MS) has advanced the study of metabolism in living
systems by allowing many metabolites to be measured in a single experiment. Although …

Since the introduction of desorption electrospray ionization (DESI) mass spectrometry (MS),
ambient MS methods have seen increased use in a variety of fields from health to food …

Eight human plasma preparation protocols were evaluated for their suitability for
metabolomic studies by ultra-high-performance liquid chromatography coupled with …

Untargeted methods are typically used in the detection and discovery of small organic
compounds in metabolomics research, and ultra-high-performance liquid chromatography …

Metabolomics is a strategy for analysis, and quantification of the complete collection of
metabolites present in biological samples. Metabolomics is an emerging area of scientific …