Multi‐omics data reveals novel impacts of human papillomavirus integration on the epigenomic and transcriptomic signatures of cervical tumorigenesis
X Zeng, Y Wang, B Liu, X Rao, C Cao… - Journal of Medical …, 2023 - Wiley Online Library
Integration of human papilloma virus (HPV) DNA into the human genome may progressively
contribute to cervical carcinogenesis. To explore how HPV integration affects gene …
contribute to cervical carcinogenesis. To explore how HPV integration affects gene …
Genomic structures and regulation patterns at HPV integration sites in cervical cancer
Human papillomavirus (HPV) integration has been implicated in transforming HPV infection
into cancer, but its genomic consequences have been difficult to study using short-read …
into cancer, but its genomic consequences have been difficult to study using short-read …
[HTML][HTML] Multiple-integrations of HPV16 genome and altered transcription of viral oncogenes and cellular genes are associated with the development of cervical …
X Lu, Q Lin, M Lin, P Duan, L Ye, J Chen, X Chen… - PLoS …, 2014 - journals.plos.org
The constitutive expression of the high-risk HPV E6 and E7 viral oncogenes is the major
cause of cervical cancer. To comprehensively explore the composition of HPV16 early …
cause of cervical cancer. To comprehensively explore the composition of HPV16 early …
Long-read sequencing reveals oncogenic mechanism of HPV-human fusion transcripts in cervical cancer
M Liu, Z Han, Y Zhi, Y Ruan, G Cao, G Wang, X Xu… - Translational …, 2023 - Elsevier
Integration of high-risk human papillomavirus (HPV) into the host genome is a crucial event
for the development of cervical cancer, however, the underlying mechanism of HPV …
for the development of cervical cancer, however, the underlying mechanism of HPV …
[HTML][HTML] Multi-omics characterization of silent and productive HPV integration in cervical cancer
J Fan, Y Fu, W Peng, X Li, Y Shen, E Guo, F Lu, S Zhou… - Cell Genomics, 2023 - cell.com
Cervical cancer (CC) that is caused by high-risk human papillomavirus (HPV) remains a
significant public health problem worldwide. HPV integration sites can be silent or actively …
significant public health problem worldwide. HPV integration sites can be silent or actively …
Characteristic of HPV integration in the genome and transcriptome of cervical cancer tissues
W Li, Y Qi, X Cui, Q Huo, L Zhu, A Zhang… - BioMed research …, 2018 - Wiley Online Library
High‐risk HPV is clearly associated with cervical cancer. HPV integration has been
confirmed to promote carcinogenesis in the previous studies. In our study, a total of 285 DNA …
confirmed to promote carcinogenesis in the previous studies. In our study, a total of 285 DNA …
Simultaneous characterization of somatic events and HPV-18 integration in a metastatic cervical carcinoma patient using DNA and RNA sequencing
WS Liang, J Aldrich, S Nasser, A Kurdoglu… - International Journal of …, 2014 - ijgc.bmj.com
Objective Integration of carcinogenic human papillomaviruses (HPVs) into the host genome
is a significant tumorigenic factor in specific cancers including cervical carcinoma. Although …
is a significant tumorigenic factor in specific cancers including cervical carcinoma. Although …
[HTML][HTML] Mechanistic signatures of HPV insertions in cervical carcinomas
A Holmes, S Lameiras, E Jeannot, Y Marie… - NPJ genomic …, 2016 - nature.com
To identify new personal biomarkers for the improved diagnosis, prognosis and biological
follow-up of human papillomavirus (HPV)-associated carcinomas, we developed a generic …
follow-up of human papillomavirus (HPV)-associated carcinomas, we developed a generic …
[HTML][HTML] HPVbase–a knowledgebase of viral integrations, methylation patterns and microRNAs aberrant expression: As potential biomarkers for Human …
A Kumar Gupta, M Kumar - Scientific reports, 2015 - nature.com
Human papillomaviruses (HPVs) are extremely associated with different carcinomas.
Despite consequential accomplishments, there is still need to establish more promising …
Despite consequential accomplishments, there is still need to establish more promising …
Multi-omics mapping of human papillomavirus integration sites illuminates novel cervical cancer target genes
M Iden, SW Tsaih, YW Huang, P Liu, M Xiao… - British Journal of …, 2021 - nature.com
Background Integration of human papillomavirus (HPV) into the host genome is a dominant
feature of invasive cervical cancer (ICC), yet the tumorigenicity of cis genomic changes at …
feature of invasive cervical cancer (ICC), yet the tumorigenicity of cis genomic changes at …
相关搜索
- cervical tumorigenesis papillomavirus integration
- transcriptomic signatures papillomavirus integration
- human papillomavirus integration
- hpv integration cervical cancer
- hpv integration cancer tissues
- hpv integration genome and transcriptome
- rna sequencing carcinoma patient
- genomic structures regulation patterns
- multi-omics mapping
- rna sequencing somatic events
- hpv human fusion transcripts
- hpv human oncogenic mechanism
- human papillomaviruses viral integrations
- cervical carcinomas mechanistic signatures
- methylation patterns viral integrations
- cervical tumorigenesis multi omics