[HTML][HTML] Renal transplantation after ex vivo normothermic perfusion: the first clinical study

ML Nicholson, SA Hosgood - American Journal of Transplantation, 2013 - Elsevier
Ex vivo normothermic perfusion (EVNP) is a novel method of preservation that restores
circulation and allows an organ to regain function prior to transplantation. The aim of this …

[HTML][HTML] Protocol of a randomised controlled, open-label trial of ex vivo normothermic perfusion versus static cold storage in donation after circulatory death renal …

SA Hosgood, K Saeb-Parsy, C Wilson, C Callaghan… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Ex vivo normothermic perfusion (EVNP) is a novel technique that reconditions
the kidney and restores renal function prior to transplantation. Phase I data from a series of …

Successful Transplantation of Human Kidneys Deemed Untransplantable but Resuscitated by Ex Vivo Normothermic Machine Perfusion

SA Hosgood, K Saeb‐Parsy, MO Hamed… - American Journal of …, 2016 - Wiley Online Library
We report the successful transplantation of a pair of human kidneys that were declined for
transplantation due to inadequate in situ perfusion but subsequently transplanted after …

Normothermic ex vivo kidney perfusion for human kidney transplantation: first North American results

LI Mazilescu, P Urbanellis, SJ Kim, T Goto… - …, 2022 - journals.lww.com
Background. Normothermic ex vivo kidney perfusion (NEVKP) has shown promising results
for preservation, assessment, and reconditioning of kidney allografts in preclinical studies …

First in man renal transplantation after ex vivo normothermic perfusion

SA Hosgood, ML Nicholson - Transplantation, 2011 - journals.lww.com
Background. Normothermic perfusion is an alternative but little studied method of organ
preservation. Herein, we report the first case of ex vivo normothermic renal transplant …

Normothermic recirculation reduces primary graft dysfunction of kidneys obtained from non‐heart‐beating donors

R Valero, C Cabrer, F Oppenheimer… - Transplant …, 2000 - Wiley Online Library
Our aim was to analyze the short‐and long‐term function of kidneys procured from non‐
heart‐beating donors (NHBD) by means of three techniques: in situ perfusion (ISP), total …

Safety and feasibility of 2 h of normothermic machine perfusion of donor kidneys in the Eurotransplant Senior Program

E Rijkse, J De Jonge, H Kimenai, MJ Hoogduijn… - BJS open, 2021 - academic.oup.com
Background The 5-year graft survival rate of donor kidneys transplanted in the
Eurotransplant Senior Program (ESP) is only 47 per cent. Normothermic machine perfusion …

Ex vivo normothermic perfusion for quality assessment of marginal donor kidney transplants

SA Hosgood, AD Barlow, JP Hunter… - Journal of British …, 2015 - academic.oup.com
Background A significant proportion of kidneys procured for transplantation are discarded
because of concerns about their suitability. In this study ex vivo normothermic perfusion …

[HTML][HTML] Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation

JM Kaths, M Hamar, J Echeverri, I Linares… - American Journal of …, 2018 - Elsevier
Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft
preservation and functional improvement in kidney transplantation. We investigated whether …

Normothermic machine perfusion of the kidney: better conditioning and repair?

SA Hosgood, E van Heurn… - Transplant …, 2015 - Wiley Online Library
Kidney transplantation is limited by hypothermic preservation techniques. Prolonged periods
of cold ischaemia increase the risk of early graft dysfunction and reduce long‐term survival …