This review focuses on the application of matrix assisted laser desorption/ionization (MALDI)
mass spectrometry to the characterization of molecules in the low mass range (< 1500 Da) …

Recent technological innovations have made proteins and nucleic acids accessible to mass
spectrometric analysis. As a result of their inherently high specificity, accuracy and …

The mass spectrometric analysis provides valuable information concerning the molecular
composition and structure of an unknown analyte and also sheds light on the quantity of a …

Sample preparation for matrix-assisted laser desorption/ionization (MALDI) mass
spectrometry (MS) of DNA is critical for obtaining high quality mass spectra. Sample impurity …

Poor detection limits and strong salt effects are two of the main problems encountered in the
matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometric …

Abstract A new MALDI–TOF based detection assay was developed for analysis of single
nucleotide polymorphisms (SNPs). It is a significant modification on the classic three‐step …

The direct analysis of tissue sections by MALDI mass spectrometry holds tremendous
potential for biomarker discovery. This technology routinely allows many hundreds of …

BACKGROUND: Mass spectrometry (MS) is becoming the gold standard for biomarker
discovery. Several MS-based bioinformatics methods have been proposed for this …

Quantitative aspects of oligonucleotide analysis by matrix‐assisted laser
desorption/ionization (MALDI) mass spectrometry remain largely unexplored relative to the …

Matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (IMS) is a
powerful tool for the generation of multidimensional spatial expression maps of …