The prevalence of obesity increased nearly eight percent over the last decade. In response
to the obesity epidemic in the United States, The National Institutes of Health Technology …

The increasing prevalence of obesity worldwide has prompted the World Health
Organization (WHO) to classify it as a global epidemic. Around the globe, more than a half …

Context: Obesity has emerged as one of the leading medical challenges of the 21st century.
The resistance of this disorder to effective, long-term treatment can be traced to the fact that …

The exceeding efforts in understanding the signals initiated by nutrients and hormones in
the central nervous system (CNS) to regulate glucose and energy homeostasis have largely …

Obesity is an increasingly prevalent and important health problem. Although treatment is
available, the long-term maintenance of medically significant weight loss (5 to 10 percent of …

The 'obesity epidemic'represents a major global socioeconomic burden that urgently calls
for a better understanding of the underlying causes of increased weight gain and its …

Our understanding of body weight regulation has been greatly advanced by the
characterization of previously existing mutations in mice that cause obesity. Subsequent …

The brain takes a primary position in the organism. We present the novel view that the brain
gives priority to controlling its own adenosine triphosphate (ATP) concentration. It fulfils this …

Although many individuals achieve weight loss of 10% or more, the ability to maintain a
reduced body mass over months and years is much rarer. Unfortunately, our understanding …

The past decade has greatly increased our understanding and appreciation of the ability of
the central nervous system (CNS) to regulate food intake and body weight. This was …