Objective Dissatisfaction with treatment and impaired quality of life (QOL) are reported
among people with treated hypothyroidism. We aimed to gain insight into this. Design and …

Background: Approximately 15% more patients taking levothyroxine (LT4) report impaired
quality of life compared to controls. This could be explained by additional diagnoses …

Introduction: This paper reports work undertaken to design two new condition-specific
questionnaires for use in hypothyroidism: the Underactive Thyroid-Dependent Quality of Life …

Background Symptoms of hypothyroidism are varied and nonspecific, thereby making
clinical diagnosis impossible. Some patients report ongoing symptoms despite treatment …

Background Disease-specific patient-reported outcome measures (PROMs) have been
developed as important research tools in the study of various diseases. For hypothyroidism …

Thyroid hormone replacement therapy (THRT, generally using oral levothyroxine (LT4)) is a
safe, effective means of treating hypothyroidism. However, a proportion of LT4-treated …

Background: Hypothyroid patients often report dissatisfaction and poor quality of life. This
survey explored the impact of hypothyroidism on patient satisfaction, everyday living …

Objectives: This article reports the psychometric properties of two new condition‐specific
questionnaires: 1) the 18‐item Underactive Thyroid‐Dependent Quality of Life …

In the 1970s, treatment with thyroid extract was superseded by levothyroxine, a synthetic l
form of tetraiodothyronine. Since then, no major innovation has emerged for the treatment of …

The aim of this study is to evaluate the frequency and relative importance of different aspects
of health related quality of life (HRQOL) impairment in patients with hypothyroidism. A survey …