[HTML][HTML] Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling
RS Phillips, SBV Ramos, PJ Blackshear - Journal of Biological Chemistry, 2002 - ASBMB
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins can bind
directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient …
directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient …
[HTML][HTML] Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element …
WS Lai, EA Kennington, PJ Blackshear - Journal of Biological Chemistry, 2002 - ASBMB
Tristetraprolin (TTP), the prototype of a small family of CCCH tandem zinc finger (TZF)
domain proteins, is a physiological stimulator of instability of the mRNAs encoding tumor …
domain proteins, is a physiological stimulator of instability of the mRNAs encoding tumor …
[HTML][HTML] Interactions of CCCH zinc finger proteins with mRNA: binding of tristetraprolin-related zinc finger proteins to AU-rich elements and destabilization of mRNA
WS Lai, E Carballo, JM Thorn, EA Kennington… - Journal of Biological …, 2000 - ASBMB
Macrophages derived from tristetraprolin (TTP)-deficient mice exhibited increased tumor
necrosis factor α (TNFα) release as a consequence of increased stability of TNFα mRNA …
necrosis factor α (TNFα) release as a consequence of increased stability of TNFα mRNA …
[HTML][HTML] Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates
PJ Blackshear, WS Lai, EA Kennington… - Journal of Biological …, 2003 - ASBMB
Tristetraprolin (TTP) and its two known mammalian family members are tandem CCCH zinc
finger proteins that can bind to AU-rich elements (AREs) in cellular mRNAs and destabilize …
finger proteins that can bind to AU-rich elements (AREs) in cellular mRNAs and destabilize …
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
WS Lai, E Carballo, JR Strum… - … and cellular biology, 1999 - Am Soc Microbiol
Mice deficient in tristetraprolin (TTP), the prototype of a family of CCCH zinc finger proteins,
develop an inflammatory syndrome mediated by excess tumor necrosis factor alpha (TNF-α) …
develop an inflammatory syndrome mediated by excess tumor necrosis factor alpha (TNF-α) …
[HTML][HTML] Interactions of CCCH zinc finger proteins with mRNA: tristetraprolin-mediated AU-rich element-dependent mRNA degradation can occur in the absence of a …
WS Lai, PJ Blackshear - Journal of Biological Chemistry, 2001 - ASBMB
The CCCH family of tandem zinc finger proteins has recently been shown to promote the
turnover of certain mRNAs containing class II AU-rich elements (AREs). In the case of one …
turnover of certain mRNAs containing class II AU-rich elements (AREs). In the case of one …
Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts
WS Lai, JS Parker, SF Grissom, DJ Stumpo… - … and cellular biology, 2006 - Taylor & Francis
Tristetraprolin (TTP) is a tandem CCCH zinc finger protein that was identified through its
rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived …
rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived …
Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover
PJ Blackshear - Biochemical Society Transactions, 2002 - portlandpress.com
The tristetraprolin (TTP) family of CCCH tandem zinc-finger proteins is composed of three
known members in mammals, with a fourth member recently identified in frogs and fish …
known members in mammals, with a fourth member recently identified in frogs and fish …
[HTML][HTML] Mutational and structural analysis of the tandem zinc finger domain of tristetraprolin
WS Lai, L Perera, SN Hicks, PJ Blackshear - Journal of Biological …, 2014 - ASBMB
Tristetraprolin (TTP), the best known member of a class of tandem (R/K) YKTELCX 8 CX 5
CX 3 H zinc finger proteins, can destabilize target mRNAs by first binding to AU-rich …
CX 3 H zinc finger proteins, can destabilize target mRNAs by first binding to AU-rich …
Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin …
DJ Stumpo, NA Byrd, RS Phillips, S Ghosh… - … and cellular biology, 2004 - Am Soc Microbiol
The mouse gene Zfp36L1 encodes zinc finger protein 36-like 1 (Zfp36L1), a member of the
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …