Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase
that is particularly abundant in the CNS. Dysregulation of GSK-3 activity is believed to play a …

Abstract Glycogen synthase kinase 3 (GSK3) is a ubiquitously expressed serine/threonine
kinase that plays a key role in the pathogenesis of Alzheimer's disease (AD). GSK3 …

Deregulation of glycogen synthase kinase‐3 (GSK‐3) activity in neurones has been
postulated as a key feature in Alzheimer's disease (AD) pathogenesis. This was further …

J. Neurochem.(2008) 104, 1433–1439. Abstract Glycogen synthase kinase 3 (GSK3) is a
constitutively active, proline‐directed serine/threonine kinase that plays a part in a number of …

Alzheimer's disease (AD) is the most common form of neurodegenerative disorder with
dementia, accounting for approximately 70% of the all cases. Currently, 5.8 million people in …

The physiological functions and pathological roles of the Glycogen synthase kinase-type 3
(GSK3) kinases in peripheral and central systems are diverse and complex, and therefore …

As a constitutively active kinase, glycogen synthase kinase 3 (GSK3) is a kinase which
regulates body metabolism by phosphorylation of glycogen synthase (GS) and other …

It has been proposed that deregulation of neuronal glycogen synthase kinase 3 (GSK3)
activity may be a key feature in Alzheimer disease pathogenesis. We have previously …

Alzheimer's disease (AD) is a common neurodegenerative disorder that presents clinically
as inexorable cognitive impairment and decline in performance of activities of daily living …

Abnormalities in molecular signalling have been implicated in neurodegeneration. It is
emerging that glycogen synthase kinase‐3 (GSK‐3) is a key signalling molecule that …