Discovered a little over two decades ago, small interfering RNAs (siRNAs) and microRNAs
(miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently …

Short or small interfering RNAs (siRNAs) and microRNA (miRNAs) are molecules similar in
size and function able to inhibit gene expression based on their complementarity with mRNA …

The approval of the first small interfering RNA (siRNA) drug Patisiran by FDA in 2018 marks
a new era of RNA interference (RNAi) therapeutics. MicroRNAs (miRNA), an important post …

In the past few years, therapeutic microRNA (miRNA) and small interfering RNA (siRNA) are
some of the most important biopharmaceuticals that are in commercial space as future …

Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to
become an essential approach in treating a variety of infectious, hemato-oncological …

MiRNAs are a conserved class of non-coding RNAs that negatively regulate gene
expression post-transcriptionally. Although their biological roles are largely unknown …

Ten years after Fire and Melo's Nobel Prize for discovery of gene silencing by double-
stranded RNA, a remarkable progress was achieved in RNA interference (RNAi). Changes …

Small interfering RNA (siRNA) and microRNA (miRNA) are small RNAs of 18-25 nucleotides
(nt) in length that play important roles in regulating gene expression. They are incorporated …

In vivo gene silencing using RNAi plays an important role in target validation and is
advancing towards the development of RNAi‐based therapeutics. RNAs were thought to …

RNA interference (RNAi) represents a promising new gene silencing technology for
functional genomics and a potential therapeutic strategy for a variety of genetic diseases …