Prediction of essential proteins using topological properties in GO-pruned PPI network based on machine learning methods
W Kim - Tsinghua Science and Technology, 2012 - ieeexplore.ieee.org
The prediction of essential proteins, the minimal set required for a living cell to support
cellular life, is an important task to understand the cellular processes of an organism. Fast …
cellular life, is an important task to understand the cellular processes of an organism. Fast …
Detecting essential proteins based on network topology, gene expression data, and gene ontology information
W Zhang, J Xu, Y Li, X Zou - IEEE/ACM transactions on …, 2016 - ieeexplore.ieee.org
The identification of essential proteins in protein-protein interaction (PPI) networks is of great
significance for understanding cellular processes. With the increasing availability of large …
significance for understanding cellular processes. With the increasing availability of large …
An iteration method for identifying yeast essential proteins from weighted PPI network based on topological and functional features of proteins
S Li, Z Chen, X He, Z Zhang, T Pei, Y Tan… - IEEE Access, 2020 - ieeexplore.ieee.org
Accumulating studies have indicated that essential proteins play critical roles in numerous
biological processes. With the rapid development of high-throughput technologies, a large …
biological processes. With the rapid development of high-throughput technologies, a large …
Identifying essential proteins from active PPI networks constructed with dynamic gene expression
Essential proteins are vitally important for cellular survival and development, and identifying
essential proteins is very meaningful research work in the post-genome era. Rapid increase …
essential proteins is very meaningful research work in the post-genome era. Rapid increase …
A novel essential protein identification method based on PPI networks and gene expression data
J Zhong, C Tang, W Peng, M Xie, Y Sun, Q Tang… - BMC …, 2021 - Springer
Background Some proposed methods for identifying essential proteins have better results by
using biological information. Gene expression data is generally used to identify essential …
using biological information. Gene expression data is generally used to identify essential …
A reliable neighbor-based method for identifying essential proteins by integrating gene expressions, orthology, and subcellular localization information
Essential proteins are those necessary for the survival or reproduction of species and
discovering such essential proteins is fundamental for understanding the minimal …
discovering such essential proteins is fundamental for understanding the minimal …
A new method for the discovery of essential proteins
Background Experimental methods for the identification of essential proteins are always
costly, time-consuming, and laborious. It is a challenging task to find protein essentiality only …
costly, time-consuming, and laborious. It is a challenging task to find protein essentiality only …
Predicting essential proteins based on weighted degree centrality
Essential proteins are vital for an organism's viability under a variety of conditions. There are
many experimental and computational methods developed to identify essential proteins …
many experimental and computational methods developed to identify essential proteins …
United complex centrality for identification of essential proteins from PPI networks
Essential proteins are indispensable for the survival or reproduction of an organism.
Identification of essential proteins is not only necessary for the understanding of the minimal …
Identification of essential proteins is not only necessary for the understanding of the minimal …
Predicting essential proteins by integrating orthology, gene expressions, and PPI networks
Identifying essential proteins is very important for understanding the minimal requirements of
cellular life and finding human disease genes as well as potential drug targets. Experimental …
cellular life and finding human disease genes as well as potential drug targets. Experimental …