Adverse health effects of urban air pollution particulates may be attributable to particle
mediated oxidant stress and inflammation. Intracellular oxidant production in normal …

Health effects associated with particulate matter (PM) show seasonal variations. We
hypothesized that these heterogeneous effects may be attributed partly to the differences in …

A number of epidemiological studies have associated increased cardiopulmonary mortality
and hospital admissions with episodes of high particulate air pollution. Inhaled particles …

We applied flow cytometric analysis to characterize the in vitro response of alveolar
macrophages (AM) to air pollution particulates. Normal hamster AM were incubated with …

Epidemiologic and occupational studies demonstrated that ambient particulate matter (PM)
and diesel exhaust particles (DEP) exert deleterious effects on human cardiopulmonary …

Epidemiologic studies have reported causal relationships between exposures to high
concentrations of ambient air particles (AAP) and increased morbidity in individuals with …

The objectives of this study were to determine whether differences in the size and
composition of coarse (2.5-10 micro m), fine (< 2.5 microm), and ultrafine (< 0.1 microm) …

It has been proposed that oxidant stress of cells in the lung is one of the underlying
mechanisms of particulate pollution-induced exacerbation of lung disease. Individuals who …

Epidemiologic studies have shown associations between ambient particulate matter (PM)
and adverse health outcomes including increased mortality, emergency room visits, and …

Macrophages and inflammatory cells generate active oxygen species in the process of
killing and degrading microorganisms. Air pollutant particles may be ingested by …